"Type C Phospholipases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of phospholipases that hydrolyze the phosphoester bond found in the third position of GLYCEROPHOSPHOLIPIDS. Although the singular term phospholipase C specifically refers to an enzyme that catalyzes the hydrolysis of PHOSPHATIDYLCHOLINE (EC 3.1.4.3), it is commonly used in the literature to refer to broad variety of enzymes that specifically catalyze the hydrolysis of PHOSPHATIDYLINOSITOLS.
Descriptor ID |
D010738
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MeSH Number(s) |
D08.811.277.352.640.700.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Type C Phospholipases".
Below are MeSH descriptors whose meaning is more specific than "Type C Phospholipases".
This graph shows the total number of publications written about "Type C Phospholipases" by people in this website by year, and whether "Type C Phospholipases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2003 | 1 | 1 | 2 |
2004 | 1 | 0 | 1 |
2006 | 0 | 2 | 2 |
2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Type C Phospholipases" by people in Profiles.
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Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes. J Physiol. 2007 Jun 15; 581(Pt 3):1113-27.
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Cell cycle-dependent calcium oscillations in mouse embryonic stem cells. Am J Physiol Cell Physiol. 2007 Apr; 292(4):C1510-8.
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Dopamine D(2) receptor modulation of K(+) channel activity regulates excitability of nucleus accumbens neurons at different membrane potentials. J Neurophysiol. 2006 Nov; 96(5):2217-28.
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Inhibition of oxidant-induced nuclear factor-kappaB activation and inhibitory-kappaBalpha degradation and instability of F-actin cytoskeletal dynamics and barrier function by epidermal growth factor: key role of phospholipase-gamma isoform. J Pharmacol Exp Ther. 2004 Apr; 309(1):356-68.
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ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J Biol Chem. 2004 Mar 12; 279(11):10042-51.
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Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly. Am J Physiol Cell Physiol. 2003 Oct; 285(4):C977-93.
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Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants. Am J Physiol Gastrointest Liver Physiol. 2001 Aug; 281(2):G412-23.
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Chondrocyte-mediated catabolism of aggrecan: evidence for a glycosylphosphatidylinositol-linked protein in the aggrecanase response to interleukin-1 or retinoic acid. Arch Biochem Biophys. 1999 Jul 15; 367(2):258-64.
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Stable expression and heterologous coupling of the kappa opioid receptor in cell lines of neural and nonneural origin. Life Sci. 1996; 58(15):1277-84.
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A novel bombesin receptor antagonist inhibits autocrine signals in a small cell lung carcinoma cell line. Biochem Biophys Res Commun. 1988 Nov 15; 156(3):1383-9.