"Claudin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously-expressed claudin subtype that acts as a general barrier-forming protein in TIGHT JUNCTIONS. Elevated expression of claudin-3 is found in a variety of tumor cell types, suggesting its role as a therapeutic target for specific ANTINEOPLASTIC AGENTS.
| Descriptor ID |
D062465
|
| MeSH Number(s) |
D12.776.543.940.200.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Claudin-3".
Below are MeSH descriptors whose meaning is more specific than "Claudin-3".
This graph shows the total number of publications written about "Claudin-3" by people in this website by year, and whether "Claudin-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Claudin-3" by people in Profiles.
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Endothelial ?-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis. Circulation. 2016 Jan 12; 133(2):177-86.