"Proton Pumps" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integral membrane proteins that transport protons across a membrane. This transport can be linked to the hydrolysis of ADENOSINE TRIPHOSPHATE. What is referred to as proton pump inhibitors frequently is about POTASSIUM HYDROGEN ATPASE.
| Descriptor ID |
D017494
|
| MeSH Number(s) |
D12.776.157.530.450.250.875 D12.776.543.585.450.250.875
|
| Concept/Terms |
Proton Pumps- Proton Pumps
- Pumps, Proton
- H+ Pump
- Pump, H+
- Proton Pump
- Pump, Proton
- H(+) Pump
|
Below are MeSH descriptors whose meaning is more general than "Proton Pumps".
Below are MeSH descriptors whose meaning is more specific than "Proton Pumps".
This graph shows the total number of publications written about "Proton Pumps" by people in this website by year, and whether "Proton Pumps" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proton Pumps" by people in Profiles.
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A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):11020-5.
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Updates on the management of upper gastrointestinal disorders in the primary care setting: NSAID-related gastropathies and pediatric reflux diseases. J Fam Pract. 2007 Mar; 56(3 Suppl Updates):S1-11; quiz S12.
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Analysis of electrophysiological properties and responses of neutrophils. Methods Mol Biol. 2007; 412:139-75.
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Endoscopy in eosinophilic esophagitis: "feline" esophagus and perforation risk. Clin Gastroenterol Hepatol. 2003 Nov; 1(6):433-7.
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The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels. Nature. 2003 Apr 03; 422(6931):531-4.
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The gp91phox component of NADPH oxidase is not a voltage-gated proton channel. J Gen Physiol. 2002 Dec; 120(6):773-9.
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Temperature dependence of voltage-gated H+ currents in human neutrophils, rat alveolar epithelial cells, and mammalian phagocytes. J Gen Physiol. 1998 Oct; 112(4):503-22.
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Na(+)-H+ antiport detected through hydrogen ion currents in rat alveolar epithelial cells and human neutrophils. J Gen Physiol. 1994 May; 103(5):755-85.