"Hemophilia B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
| Descriptor ID |
D002836
|
| MeSH Number(s) |
C15.378.100.100.510 C15.378.100.141.510 C15.378.463.510 C16.320.099.510 C16.320.322.235
|
| Concept/Terms |
Hemophilia B- Hemophilia B
- Bs, Hemophilia
- Hemophilia Bs
- Deficiency, Factor IX
- Deficiencies, Factor IX
- Factor IX Deficiencies
- Factor IX Deficiency
- Hemophilia B Leyden
- Hemophilia B(M)
- Hemophilia Bs (M)
- Plasma Thromboplastin Component Deficiency
- F9 Deficiency
- Deficiencies, F9
- Deficiency, F9
- F9 Deficiencies
- Christmas Disease
- Disease, Christmas
- Haemophilia B
- Haemophilia Bs
|
Below are MeSH descriptors whose meaning is more general than "Hemophilia B".
Below are MeSH descriptors whose meaning is more specific than "Hemophilia B".
This graph shows the total number of publications written about "Hemophilia B" by people in this website by year, and whether "Hemophilia B" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Hemophilia B" by people in Profiles.
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High adherence to prophylaxis regimens in haemophilia B patients receiving rIX-FP: Evidence from clinical trials and real-world practice. Haemophilia. 2020 Jul; 26(4):637-642.
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Patient-reported outcomes and joint status across subgroups of US adults with hemophilia with varying characteristics: Results from the Pain, Functional Impairment, and Quality of Life (P-FiQ) study. Eur J Haematol. 2018 Apr; 100 Suppl 1:14-24.
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Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors. Haemophilia. 2017 Nov; 23(6):844-851.
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Bypassing agent prophylaxis in people with hemophilia A or B with inhibitors. Cochrane Database Syst Rev. 2017 09 25; 9:CD011441.
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PERSEPT 1: a phase 3 trial of activated eptacog beta for on-demand treatment of haemophilia inhibitor-related bleeding. Haemophilia. 2017 Nov; 23(6):832-843.
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Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial. Blood. 2016 04 07; 127(14):1761-9.
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Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice. EMBO Mol Med. 2013 11; 5(11):1684-97.
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Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX. Blood. 2008 Dec 01; 112(12):4532-41.
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Retroperitoneal amyloidosis, factor IX and X deficiency,and gastrointestinal bleeding. Abdom Imaging. 1996 May-Jun; 21(3):266-8.