Granulomatous Disease, Chronic
"Granulomatous Disease, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
| Descriptor ID |
D006105
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| MeSH Number(s) |
C15.378.553.774.535 C16.320.322.233 C20.673.774.535
|
| Concept/Terms |
Granulomatous Disease, Chronic- Granulomatous Disease, Chronic
- Chronic Granulomatous Diseases
- Granulomatous Diseases, Chronic
- Chronic Granulomatous Disease
Granulomatous Disease, Chronic, X-Linked- Granulomatous Disease, Chronic, X-Linked
- Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked
- X-Linked Chronic Granulomatous Disease
- X Linked Chronic Granulomatous Disease
- Granulomatous Disease, Chronic, X-Linked, Variant
- Chronic Granulomatous Disease, Atypical
- Chronic Granulomatous Disease, X-Linked
- Chronic Granulomatous Disease, X Linked
- Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked
|
Below are MeSH descriptors whose meaning is more general than "Granulomatous Disease, Chronic".
Below are MeSH descriptors whose meaning is more specific than "Granulomatous Disease, Chronic".
This graph shows the total number of publications written about "Granulomatous Disease, Chronic" by people in this website by year, and whether "Granulomatous Disease, Chronic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Granulomatous Disease, Chronic" by people in Profiles.
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Persistent Pneumonia in an Infant. Pediatrics. 2015 Jul; 136(1):154-60.
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Muscle and nerve involvement in granulomatous mycosis fungoides. Muscle Nerve. 2007 Dec; 36(6):860-5.
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The pH dependence of NADPH oxidase in human eosinophils. J Physiol. 2005 Dec 01; 569(Pt 2):419-31.
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The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps. J Biol Chem. 2001 Sep 28; 276(39):36063-6.
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Evaluation of human monocyte oxidative metabolism utilizing a flow cytometric assay. Clin Exp Immunol. 1989 Oct; 78(1):91-6.