"CRISPR-Cas Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS.
| Descriptor ID |
D064113
|
| MeSH Number(s) |
G05.308.203.374.394
|
| Concept/Terms |
CRISPR-Cas Systems- CRISPR-Cas Systems
- CRISPR Cas Systems
- CRISPR-Cas System
- System, CRISPR-Cas
- Systems, CRISPR-Cas
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Cas Systems".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Cas Systems".
This graph shows the total number of publications written about "CRISPR-Cas Systems" by people in this website by year, and whether "CRISPR-Cas Systems" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "CRISPR-Cas Systems" by people in Profiles.
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CRISPR-mediated Sox9 activation and RelA inhibition enhance cell therapy for osteoarthritis. Mol Ther. 2024 Aug 07; 32(8):2549-2562.
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Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467.
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Expression and function of voltage gated proton channels (Hv1) in MDA-MB-231 cells. PLoS One. 2020; 15(5):e0227522.
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A Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases. J Neuroimmune Pharmacol. 2019 12; 14(4):534-536.
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Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis. Ann Rheum Dis. 2019 05; 78(5):676-682.
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A CRISPR focus on attitudes and beliefs toward somatic genome editing from stakeholders within the sickle cell disease community. Genet Med. 2019 08; 21(8):1726-1734.
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The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation. J Cell Physiol. 2015 Nov; 230(11):2683-94.