Homer Scaffolding Proteins
"Homer Scaffolding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.
Descriptor ID |
D000072233
|
MeSH Number(s) |
D12.776.476.024.381
|
Concept/Terms |
Homer Scaffolding Proteins- Homer Scaffolding Proteins
- Proteins, Homer Scaffolding
- Scaffolding Proteins, Homer
- Homer Proteins
- Proteins, Homer
Homer 1C- Homer 1C
- Homer 1C Proteins
- Proteins, Homer 1C
Homer 3- Homer 3
- Homer 3 Proteins
- Proteins, Homer 3
Homer 2- Homer 2
- Homer 2 Proteins
- Proteins, Homer 2
Homer 1a- Homer 1a
- Homer 1 Proteins
- Proteins, Homer 1
|
Below are MeSH descriptors whose meaning is more general than "Homer Scaffolding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Homer Scaffolding Proteins".
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