Last Name

Sumant S. Chugh

InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Nephrology
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    My Scopus ID is 55330649200.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Del Nogal-Avila M, Donoro-Blazquez H, Saha MK, Marshall CB, Clement LC, Macé CE, Chugh SS. Novel therapeutic approaches for chronic kidney disease due to glomerular disorders. Am J Physiol Renal Physiol. 2016 07 01; 311(1):F63-5. PMID: 27147672.
      View in: PubMed
    2. Clement LC, Macé C, Del Nogal Avila M, Marshall CB, Chugh SS. The proteinuria-hypertriglyceridemia connection as a basis for novel therapeutics for nephrotic syndrome. Transl Res. 2015 Apr; 165(4):499-504. PMID: 25005737.
      View in: PubMed
    3. Macé C, Chugh SS. Nephrotic syndrome: components, connections, and angiopoietin-like 4-related therapeutics. J Am Soc Nephrol. 2014 Nov; 25(11):2393-8. PMID: 24854282; PMCID: PMC4214538.
    4. Wiggins RC, Alpers CE, Holzman LB, He JC, Salant DJ, Chugh SS, Natarajan R, Trachtman H, Brasile L, Star RA, Rys-Sikora KE, Moxey-Mims MM, Flessner MF. Glomerular disease: looking beyond pathology. Clin J Am Soc Nephrol. 2014 Jun 06; 9(6):1138-40. PMID: 24700796; PMCID: PMC4046719.
    5. Chugh SS, Macé C, Clement LC, Del Nogal Avila M, Marshall CB. Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease. Front Pharmacol. 2014; 5:23. PMID: 24611049; PMCID: PMC3933785.
    6. Clement LC, Macé C, Avila-Casado C, Joles JA, Kersten S, Chugh SS. Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 2014 Jan; 20(1):37-46. PMID: 24317117; PMCID: PMC4114723.
    7. Li S, Nagothu K, Ranganathan G, Ali SM, Shank B, Gokden N, Ayyadevara S, Megyesi J, Olivecrona G, Chugh SS, Kersten S, Portilla D. Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F437-48. PMID: 22622461; PMCID: PMC3433869.
    8. Chugh SS, Clement LC. Telomerase at the center of collapsing glomerulopathy. Nat Med. 2012 Jan 06; 18(1):26-7. PMID: 22227662; PMCID: PMC4114573.
    9. Chugh SS, Clement LC, Macé C. New insights into human minimal change disease: lessons from animal models. Am J Kidney Dis. 2012 Feb; 59(2):284-92. PMID: 21974967; PMCID: PMC3253318.
    10. Avila-Casado C, Fortoul TI, Chugh SS. HIV-associated nephropathy: experimental models. Contrib Nephrol. 2011; 169:270-85. PMID: 21252526.
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    11. Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS. Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 2011 Jan; 17(1):117-22. PMID: 21151138; PMCID: PMC3021185.
    12. Saxena N, Chugh SS, Centor R. Coagulase-negative staphylococcus-oftentimes a virulent masquerader. NDT Plus. 2011 Feb; 4(1):81-2. PMID: 25984117; PMCID: PMC4421623.
    13. Bell EK, Chugh SS, Cook WJ. A case of infection-associated antiproteinase-3-negative cytoplasmic antineutrophil cytoplasmic antibody pauci-immune focal necrotizing glomerulonephritis. Nephrol Dial Transplant. 2010 Sep; 25(9):3119-23. PMID: 20566570; PMCID: PMC2948835.
    14. Sun L, Xie P, Wada J, Kashihara N, Liu FY, Zhao Y, Kumar D, Chugh SS, Danesh FR, Kanwar YS. Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction. J Am Soc Nephrol. 2008 Dec; 19(12):2293-301. PMID: 18753253; PMCID: PMC2588105.
    15. Kanwar YS, Wada J, Sun L, Xie P, Wallner EI, Chen S, Chugh S, Danesh FR. Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood). 2008 Jan; 233(1):4-11. PMID: 18156300.
      View in: PubMed
    16. Kanwar YS, Danesh FR, Chugh SS. Chimerism of the renal glomerulus revisited. J Am Soc Nephrol. 2007 Aug; 18(8):2215-7. PMID: 17625114.
      View in: PubMed
    17. Kanwar YS, Danesh FR, Chugh SS. Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective. Am J Pathol. 2007 Jul; 171(1):9-13. PMID: 17591948; PMCID: PMC1941605.
    18. Chugh SS. Transcriptional regulation of podocyte disease. Transl Res. 2007 May; 149(5):237-42. PMID: 17466922; PMCID: PMC1974875.
    19. Clement LC, Liu G, Perez-Torres I, Kanwar YS, Avila-Casado C, Chugh SS. Early changes in gene expression that influence the course of primary glomerular disease. Kidney Int. 2007 Aug; 72(3):337-47. PMID: 17457373.
      View in: PubMed
    20. Liu G, Clement LC, Kanwar YS, Avila-Casado C, Chugh SS. ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. J Biol Chem. 2006 Dec 22; 281(51):39681-92. PMID: 17056598.
      View in: PubMed
    21. Nayak B, Xie P, Akagi S, Yang Q, Sun L, Wada J, Thakur A, Danesh FR, Chugh SS, Kanwar YS. Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):17952-7. PMID: 16330753; PMCID: PMC1312416.
    22. Kanwar YS, Akagi S, Nayak B, Sun L, Wada J, Xie P, Thakur A, Chugh SS, Danesh FR. Renal-specific oxidoreductase biphasic expression under high glucose ambience during fetal versus neonatal development. Kidney Int. 2005 Oct; 68(4):1670-83. PMID: 16164644.
      View in: PubMed
    23. Schafernak KT, Chugh SS, Kanwar YS. Co-existent crescentic glomerulonephritis and renal amyloidosis: a case report and literature review. J Nephrol. 2005 Sep-Oct; 18(5):616-22. PMID: 16299691.
      View in: PubMed
    24. Kanwar YS, Akagi S, Sun L, Nayak B, Xie P, Wada J, Chugh SS, Danesh FR. Cell biology of diabetic kidney disease. Nephron Exp Nephrol. 2005; 101(3):e100-10. PMID: 16088221.
      View in: PubMed
    25. Kanwar YS, Nayak B, Lin S, Akagi S, Xie P, Wada J, Chugh SS, Danesh FR. Hyperglycemia: its imminent effects on mammalian nephrogenesis. Pediatr Nephrol. 2005 Jul; 20(7):858-66. PMID: 15875217.
      View in: PubMed
    26. Kanwar YS, Wada J, Lin S, Danesh FR, Chugh SS, Yang Q, Banerjee T, Lomasney JW. Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F202-15. PMID: 14707006.
      View in: PubMed
    27. Chugh SS, Wallner EI, Kanwar YS. Renal development in high-glucose ambience and diabetic embryopathy. Semin Nephrol. 2003 Nov; 23(6):583-92. PMID: 14631566.
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    28. Chugh SS, Kaw B, Kanwar YS. Molecular structure-function relationship in the slit diaphragm. Semin Nephrol. 2003 Nov; 23(6):544-55. PMID: 14631562.
      View in: PubMed
    29. Liu G, Kaw B, Kurfis J, Rahmanuddin S, Kanwar YS, Chugh SS. Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. J Clin Invest. 2003 Jul; 112(2):209-21. PMID: 12865409; PMCID: PMC164293.
    30. Lin S, Sahai A, Chugh SS, Pan X, Wallner EI, Danesh FR, Lomasney JW, Kanwar YS. High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. J Biol Chem. 2002 Nov 01; 277(44):41725-35. PMID: 12196513.
      View in: PubMed
    31. Sun L, Pan X, Wada J, Haas CS, Wuthrich RP, Danesh FR, Chugh SS, Kanwar YS. Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy. J Biol Chem. 2002 Aug 16; 277(33):29953-62. PMID: 12171997.
      View in: PubMed
    32. Kanwar YS, Kumar A, Ota K, Lin S, Wada J, Chugh S, Wallner EI. Identification of developmentally regulated mesodermal-specific transcript in mouse embryonic metanephros. Am J Physiol Renal Physiol. 2002 May; 282(5):F953-65. PMID: 11934706.
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    33. Kanwar YS, Yang Q, Tian Y, Lin S, Wada J, Chugh S, Srivastava SK. Relevance of renal-specific oxidoreductase in tubulogenesis during mammalian nephron development. Am J Physiol Renal Physiol. 2002 Apr; 282(4):F752-62. PMID: 11880337.
      View in: PubMed
    34. Wallner EI, Wada J, Lin S, Pan X, Reddy JK, Chugh SS, Kanwar YS. Renal gene expression in embryonic and newborn diabetic mice. Exp Nephrol. 2002; 10(2):130-8. PMID: 11937760.
      View in: PubMed
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