"Nephrotic Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Descriptor ID |
D009404
|
| MeSH Number(s) |
C12.777.419.630.643 C13.351.968.419.630.643
|
| Concept/Terms |
Nephrotic Syndrome- Nephrotic Syndrome
- Nephrotic Syndromes
- Syndrome, Nephrotic
- Syndromes, Nephrotic
|
Below are MeSH descriptors whose meaning is more general than "Nephrotic Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Nephrotic Syndrome".
This graph shows the total number of publications written about "Nephrotic Syndrome" by people in this website by year, and whether "Nephrotic Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nephrotic Syndrome" by people in Profiles.
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"Idiopathic" minimal change nephrotic syndrome: a podocyte mystery nears the end. Am J Physiol Renal Physiol. 2023 12 01; 325(6):F685-F694.
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Secretion of the epithelial sodium channel chaperone PCSK9 from the cortical collecting duct links sodium retention with hypercholesterolemia in nephrotic syndrome. Kidney Int. 2020 12; 98(6):1449-1460.
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Management of Adult Minimal Change Disease. Clin J Am Soc Nephrol. 2019 06 07; 14(6):911-913.
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The proteinuria-hypertriglyceridemia connection as a basis for novel therapeutics for nephrotic syndrome. Transl Res. 2015 Apr; 165(4):499-504.
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Nephrotic syndrome: components, connections, and angiopoietin-like 4-related therapeutics. J Am Soc Nephrol. 2014 Nov; 25(11):2393-8.
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Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 2014 Jan; 20(1):37-46.
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Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 2011 Jan; 17(1):117-22.
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ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. J Biol Chem. 2006 Dec 22; 281(51):39681-92.
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Angiotensin antagonists and steroids in the treatment of focal segmental glomerulosclerosis. Semin Nephrol. 2003 Mar; 23(2):219-28.
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Focal segmental glomerulosclerosis: prognostic implications of the cellular lesion. J Am Soc Nephrol. 1999 Sep; 10(9):1900-7.