 Apoptosis
"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
| Descriptor ID |
D017209
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| MeSH Number(s) |
G04.299.139.160
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| Concept/Terms |
Apoptosis- Apoptosis
- Programmed Cell Death, Type I
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Below are MeSH descriptors whose meaning is more general than "Apoptosis".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis".
This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 5 | 3 | 8 | | 1997 | 1 | 4 | 5 | | 1998 | 2 | 2 | 4 | | 1999 | 6 | 3 | 9 | | 2000 | 3 | 1 | 4 | | 2001 | 5 | 3 | 8 | | 2002 | 5 | 4 | 9 | | 2003 | 6 | 5 | 11 | | 2004 | 6 | 7 | 13 | | 2005 | 2 | 8 | 10 | | 2006 | 3 | 2 | 5 | | 2007 | 9 | 4 | 13 | | 2008 | 3 | 4 | 7 | | 2009 | 4 | 2 | 6 | | 2010 | 2 | 5 | 7 | | 2011 | 3 | 6 | 9 | | 2012 | 3 | 6 | 9 | | 2013 | 5 | 8 | 13 | | 2014 | 3 | 10 | 13 | | 2015 | 1 | 6 | 7 | | 2016 | 0 | 3 | 3 | | 2017 | 1 | 7 | 8 | | 2018 | 2 | 7 | 9 | | 2019 | 1 | 3 | 4 | | 2020 | 1 | 4 | 5 | | 2021 | 1 | 4 | 5 | | 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Apoptosis" by people in Profiles.
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Ly L, Cheng X, Murthy SRK, Jones OZ, Zhuang T, Gitelis S, Blank AT, Nissan A, Adileh M, Colman M, Keidar M, Basadonna G, Canady J. Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation, Disrupting Cell Cycle, and Inducing Apoptosis: A Preliminary Report. Molecules. 2022 Jun 29; 27(13).
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Li GM, Chen JR, Zhang HQ, Sun C, Chen GR, Xiong QY, Cao XY, Yu L, Lin ZW, Qin JY, Wu LJ, Li J, Pu L, Peng F, Xie XF, Peng C. Rhein activated Fas-induced apoptosis pathway causing cardiotoxicity in vitro and in vivo. Toxicol Lett. 2022 Jun 15; 363:67-76.
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Mohamed MF, Al-Khudari S, Cassini-Vieira P, Erra A, Bagabas R, Houser T, Stenson K, Bhayani M, Jelinek MJ, Bishehsari F, Kuzel TM, Shafikhani SH. Presence of CrkI-containing microvesicles in squamous cell carcinomas could have ramifications on tumor biology and cancer therapeutics. Sci Rep. 2022 03 21; 12(1):4803.
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Cong S, Liu Y, Li Y, Chen Y, Chen R, Zhang B, Yu L, Hu Y, Zhao X, Mu M, Cheng M, Huang Z. MiR-571 affects the development and progression of liver fibrosis by regulating the Notch3 pathway. Sci Rep. 2021 11 08; 11(1):21854.
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Usha L, Klapko O, Edassery S. Xenogeneic fibroblasts inhibit the growth of the breast and ovarian cancer cell lines in co-culture. Neoplasma. 2021 Nov; 68(6):1265-1271.
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Dai J, Zha Y, Foster CC, Luke JJ, Chmura SJ, Hoffman MD. Punctate Anetoderma After Colony-Stimulating Factor 1 Receptor and Programmed Cell Death 1 Blockade With Irradiation: Clinicopathologic Characterization of a Novel Eruption. JAMA Dermatol. 2021 08 01; 157(8):998-1000.
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Zhao J, Schank M, Wang L, Li Z, Nguyen LN, Dang X, Cao D, Khanal S, Nguyen LNT, Thakuri BKC, Ogbu SC, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Liu Y, Zhang J, Ning S, Moorman JP, Yao ZQ. Mitochondrial Functions Are Compromised in CD4 T Cells From ART-Controlled PLHIV. Front Immunol. 2021; 12:658420.
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Akbarian F, Dadkhah F, Campbell A, Asadi F, Ahangari G. Characterization of Dopamine Receptor Associated Drugs on the Proliferation and Apoptosis of Prostate Cancer Cell Lines. Anticancer Agents Med Chem. 2021; 21(9):1160-1171.
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Lin AY, Rink JS, Karmali R, Xu J, Kocherginsky M, Thaxton CS, Gordon LI. Tri-ethylene glycol modified class B and class C CpG conjugated gold nanoparticles for the treatment of lymphoma. Nanomedicine. 2020 11; 30:102290.
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Yu L, Shang D, Lang L, Liu Y, Yu M, Song D, Jia S, Han S, Li C, Liu J, Xu Y, Zhang X. TMF, a natural dihydroflavonoid isolated from Scutellaria javanica Jungh, stimulates anticancer activity of s180 cancer-bearing mice, induces apoptosis, inhibits invasion and migration on HepG-2 cells. J Ethnopharmacol. 2020 Dec 05; 263:113072.
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