"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Involvement of Cryptosporidium parvum Cdg7_FLc_1000 RNA in the Attenuation of Intestinal Epithelial Cell Migration via Trans-Suppression of Host Cell SMPD3. J Infect Dis. 2017 Dec 27; 217(1):122-133.
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A long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-?B to modulate inflammatory gene transcription in mouse macrophages. FASEB J. 2017 Mar; 31(3):1215-1225.
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The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review. PLoS One. 2016; 11(12):e0167201.
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LincRNA-Cox2 modulates TNF-a-induced transcription of Il12b gene in intestinal epithelial cells through regulation of Mi-2/NuRD-mediated epigenetic histone modifications. FASEB J. 2016 Mar; 30(3):1187-97.
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Epigenomics of Alzheimer's disease. Transl Res. 2015 Jan; 165(1):200-20.
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MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction. J Am Soc Nephrol. 2014 Aug; 25(8):1698-709.
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Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models. Arthritis Rheum. 2013 Jul; 65(7):1725-35.
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Histone deacetylases and NF-kB signaling coordinate expression of CX3CL1 in epithelial cells in response to microbial challenge by suppressing miR-424 and miR-503. PLoS One. 2013; 8(5):e65153.
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Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. Br J Haematol. 2010 Jan; 148(1):69-79.
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Abnormalities of molecular regulators of proliferation and apoptosis in carcinoma of the oral cavity and oropharynx. Auris Nasus Larynx. 2002 Apr; 29(2):165-74.