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Ryan Ross

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentCell and Molecular Medicine
AddressChicago IL 60612
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    Collapse Overview 
    Collapse overview
    My Scopus ID is 22433638000.
    My NIH COMMONS name is RROSS84.

    Research Areas:
    Dr. Ross’ research is focused in two areas: skeletal mineralization and circulating biomarkers. Mineralization is the final step in the bone formation phase, providing the skeleton with its characteristic mechanical properties. Despite its importance to the overall function of the skeletal, it remains poorly understood and difficult to study. Dr. Ross’ lab is currently working to develop a novel small animal model to study mineralization. Once this model is fully validated, it can be used to develop a new understanding of the mineralization process and the effect that various drugs, genes, and nutritional factors have on mineralization.

    Dr. Ross has also been working on various projects related to the use of circulating biomarkers as diagnostic tools. These markers may help identify patients suffering from diseases, such as peri-implant osteolysis prior to current clinical diagnoses, widening the treatment window and preventing subsequent revision surgeries.

    My Faculty Profile at Rush University Medical Center:
    https://www.rushu.rush.edu/faculty/ryan-ross-phd

    My Laboratory:
    https://www.rushu.rush.edu/research/departmental-research/cell-molecular-medicine-research/laboratory-ryan-ross-phd

    My NCBI Bibliography:
    https://www.ncbi.nlm.nih.gov/myncbi/1rGK7HaDKlcAE/bibliography/public/

    My Scopus:
    https://www.scopus.com/authid/detail.uri?authorId=22433638000

    Education:
    PhD, University of Notre Dame


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wilson BM, Moran MM, Meagher MJ, Ross RD, Mashiatulla M, Virdi AS, Sumner DR. Early changes in serum osteocalcin and body weight are predictive of implant fixation in a rat model of implant loosening. J Orthop Res. 2020 Jun; 38(6):1216-1227. PMID: 31825107.
      View in: PubMed
    2. Ko FC, Meagher MJ, Mashiatulla M, Ross RD, Virdi AS, Sumner DR. Implant surface alters compartmental-specific contributions to fixation strength in rats. J Orthop Res. 2020 Jun; 38(6):1208-1215. PMID: 31821588.
      View in: PubMed
    3. Carpenter KA, Ross RD. Sclerostin Antibody Treatment Increases Bone Mass and Normalizes Circulating Phosphate Levels in Growing Hyp Mice. J Bone Miner Res. 2020 Mar; 35(3):596-607. PMID: 31743490.
      View in: PubMed
    4. Shen Q, Li J, Chan D, Sandy JD, Takeuchi J, Ross RD, Plaas A. Effect of intra-articular hyaluronan injection on inflammation and bone remodeling in the epiphyses and metaphyses of the knee in a murine model of joint injury. Am J Transl Res. 2019; 11(6):3280-3300. PMID: 31312344.
      View in: PubMed
    5. Ross RD, Shah RC, Leurgans S, Bottiglieri T, Wilson RS, Sumner DR. Circulating Dkk1 and TRAIL Are Associated With Cognitive Decline in Community-Dwelling, Older Adults With Cognitive Concerns. J Gerontol A Biol Sci Med Sci. 2018 11 10; 73(12):1688-1694. PMID: 29432613.
      View in: PubMed
    6. Ross RD, Meagher MJ, Sumner DR. Calcium restriction during lactation has minimal effects on post-weaning mineral metabolism and bone recovery. J Bone Miner Metab. 2019 Jul; 37(4):648-657. PMID: 30361872.
      View in: PubMed
    7. Witcher PC, Miner SE, Horan DJ, Bullock WA, Lim KE, Kang KS, Adaniya AL, Ross RD, Loots GG, Robling AG. Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition. JCI Insight. 2018 06 07; 3(11). PMID: 29875318.
      View in: PubMed
    8. Ross RD, Deng Y, Fang R, Frisch NB, Jacobs JJ, Sumner DR. Discovery of biomarkers to identify peri-implant osteolysis before radiographic diagnosis. J Orthop Res. 2018 10; 36(10):2754-2761. PMID: 29873110.
      View in: PubMed
    9. Ross RD, Sumner DR. Erratum to: Bone Matrix Maturation in a Rat Model of Intra-Cortical Bone Remodeling. Calcif Tissue Int. 2017 08; 101(2):204-206. PMID: 28455562.
      View in: PubMed
    10. Moran MM, Wilson BM, Ross RD, Virdi AS, Sumner DR. Arthrotomy-based preclinical models of particle-induced osteolysis: A systematic review. J Orthop Res. 2017 12; 35(12):2595-2605. PMID: 28548682.
      View in: PubMed
    11. Ross RD, Sumner DR. Bone Matrix Maturation in a Rat Model of Intra-Cortical Bone Remodeling. Calcif Tissue Int. 2017 08; 101(2):193-203. PMID: 28374176.
      View in: PubMed
    12. Mashiatulla M, Ross RD, Sumner DR. Validation of cortical bone mineral density distribution using micro-computed tomography. Bone. 2017 06; 99:53-61. PMID: 28363808.
      View in: PubMed
    13. Ross RD, Mashiatulla M, Acerbo AS, Almer JD, Miller LM, Johnson ML, Sumner DR. HBM Mice Have Altered Bone Matrix Composition and Improved Material Toughness. Calcif Tissue Int. 2016 10; 99(4):384-95. PMID: 27230741.
      View in: PubMed
    14. Ross RD, Mashiatulla M, Robling AG, Miller LM, Sumner DR. Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status. Calcif Tissue Int. 2016 Feb; 98(2):149-57. PMID: 26514840.
      View in: PubMed
    15. Elangovan S, Khorsand B, Do AV, Hong L, Dewerth A, Kormann M, Ross RD, Sumner DR, Allamargot C, Salem AK. Chemically modified RNA activated matrices enhance bone regeneration. J Control Release. 2015 Nov 28; 218:22-8. PMID: 26415855.
      View in: PubMed
    16. D'Mello SR, Elangovan S, Hong L, Ross RD, Sumner DR, Salem AK. A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects. Curr Pharm Biotechnol. 2015; 16(7):655-60. PMID: 25934975.
      View in: PubMed
    17. D'Mello S, Elangovan S, Hong L, Ross RD, Sumner DR, Salem AK. Incorporation of copper into chitosan scaffolds promotes bone regeneration in rat calvarial defects. J Biomed Mater Res B Appl Biomater. 2015 Jul; 103(5):1044-9. PMID: 25230382.
      View in: PubMed
    18. Kousik SM, Napier TC, Ross RD, Sumner DR, Carvey PM. Dopamine receptors and the persistent neurovascular dysregulation induced by methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2014 Nov; 351(2):432-9. PMID: 25185214.
      View in: PubMed
    19. Ross RD, Edwards LH, Acerbo AS, Ominsky MS, Virdi AS, Sena K, Miller LM, Sumner DR. Bone matrix quality after sclerostin antibody treatment. J Bone Miner Res. 2014 Jul; 29(7):1597-607. PMID: 24470143.
      View in: PubMed
    20. Ross RD, Virdi AS, Liu S, Sena K, Sumner DR. Particle-induced osteolysis is not accompanied by systemic remodeling but is reflected by systemic bone biomarkers. J Orthop Res. 2014 Jul; 32(7):967-73. PMID: 24604767.
      View in: PubMed
    21. Ross RD, Hamilton JL, Wilson BM, Sumner DR, Virdi AS. Pharmacologic augmentation of implant fixation in osteopenic bone. Curr Osteoporos Rep. 2014 Mar; 12(1):55-64. PMID: 24293098.
      View in: PubMed
    22. Elangovan S, D'Mello SR, Hong L, Ross RD, Allamargot C, Dawson DV, Stanford CM, Johnson GK, Sumner DR, Salem AK. The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor. Biomaterials. 2014 Jan; 35(2):737-47. PMID: 24161167.
      View in: PubMed
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