 Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
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| MeSH Number(s) |
D05
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1994 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Yang S, Ajilore O, Wu M, Lamar M, Kumar A. Impaired macromolecular protein pools in fronto-striato-thalamic circuits in type 2 diabetes revealed by magnetization transfer imaging. Diabetes. 2015 Jan; 64(1):183-92.
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Martin EJ, Pourzal R, Mathew MT, Shull KR. Dominant role of molybdenum in the electrochemical deposition of biological macromolecules on metallic surfaces. Langmuir. 2013 Apr 16; 29(15):4813-22.
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Bonomi P. Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer. Expert Rev Anticancer Ther. 2007 Apr; 7(4):415-22.
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Seog J, Dean D, Rolauffs B, Wu T, Genzer J, Plaas AH, Grodzinsky AJ, Ortiz C. Nanomechanics of opposing glycosaminoglycan macromolecules. J Biomech. 2005 Sep; 38(9):1789-97.
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Ng L, Grodzinsky AJ, Patwari P, Sandy J, Plaas A, Ortiz C. Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy. J Struct Biol. 2003 Sep; 143(3):242-57.
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Barker E, Bossart KN, Fujimura SH, Levy JA. The role of CD80 and CD86 in enhancing CD8(+) cell suppression of HIV replication. Cell Immunol. 1999 Sep 15; 196(2):95-103.
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F?l?p C, Kamath RV, Li Y, Otto JM, Salustri A, Olsen BR, Glant TT, Hascall VC. Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes. Gene. 1997 Nov 20; 202(1-2):95-102.
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Banerjee P, Boyers MJ, Berry-Kravis E, Dawson G. Preferential beta-hexosaminidase (Hex) A (alpha beta) formation in the absence of beta-Hex B (beta beta) due to heterozygous point mutations present in beta-Hex beta-chain alleles of a motor neuron disease patient. J Biol Chem. 1994 Feb 18; 269(7):4819-26.
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Ma J, Guti?rrez LM, Hosey MM, R?os E. Dihydropyridine-sensitive skeletal muscle Ca channels in polarized planar bilayers. 3. Effects of phosphorylation by protein kinase C. Biophys J. 1992 Sep; 63(3):639-47.
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Karnik NS, Newman S, Kopf GS, Gerton GL. Developmental expression of G protein alpha subunits in mouse spermatogenic cells: evidence that G alpha i is associated with the developing acrosome. Dev Biol. 1992 Aug; 152(2):393-402.
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