"Macrophage-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
| Descriptor ID |
D016177
|
| MeSH Number(s) |
D12.776.543.750.705.408.495.500 D12.776.543.750.705.408.600.500 D12.776.543.750.705.833.500
|
| Concept/Terms |
Macrophage-1 Antigen- Macrophage-1 Antigen
- Antigen, Macrophage-1
- Macrophage 1 Antigen
- CR3 Receptor
- Receptor, CR3
- Mo1 Antigen Receptor
- Antigen Receptor, Mo1
- Receptor, Mo1 Antigen
- Mo1 Glycoprotein Receptor
- Glycoprotein Receptor, Mo1
- Receptor, Mo1 Glycoprotein
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alpha M beta 2
- alpha-M beta-2, Integrin
- Complement 3 Receptor
- Receptor, Complement 3
- Mac-1 Antigen
- Mac 1 Antigen
- Adhesive Receptor Mac-1
- Mac-1 Adhesive Receptor
- Adhesive Receptor, Mac-1
- Mac 1 Adhesive Receptor
- Receptor, Mac-1 Adhesive
- Mac-1 Receptor
- Mac 1 Receptor
- Integrin alphaMbeta2
- alphaMbeta2, Integrin
|
Below are MeSH descriptors whose meaning is more general than "Macrophage-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-1 Antigen".
This graph shows the total number of publications written about "Macrophage-1 Antigen" by people in this website by year, and whether "Macrophage-1 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage-1 Antigen" by people in Profiles.
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Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal ?-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response. J Immunol. 2017 01 01; 198(1):318-334.
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An anti-inflammatory property of Candida albicans ?-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Cytokine. 2015 Feb; 71(2):215-22.
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Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. J Clin Invest. 2014 Apr; 124(4):1483-96.
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Extracellular protein disulfide isomerase regulates ligand-binding activity of aM?2 integrin and neutrophil recruitment during vascular inflammation. Blood. 2013 May 09; 121(19):3789-800, S1-15.
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Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal. 2011 Sep 06; 4(189):ra57.
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Identification of pH-regulated antigen 1 released from Candida albicans as the major ligand for leukocyte integrin alphaMbeta2. J Immunol. 2007 Feb 15; 178(4):2038-46.
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Lymphocyte adhesion to Candida albicans. Infect Immun. 2002 Feb; 70(2):517-27.
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Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol. 1999 Mar; 94(3):704-12.
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Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602.