 Macrophage-1 Antigen
"Macrophage-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
| Descriptor ID |
D016177
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| MeSH Number(s) |
D12.776.543.750.705.408.495.500 D12.776.543.750.705.408.600.500 D12.776.543.750.705.833.500
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| Concept/Terms |
Macrophage-1 Antigen- Macrophage-1 Antigen
- Antigen, Macrophage-1
- Macrophage 1 Antigen
- CR3 Receptor
- Receptor, CR3
- Mo1 Antigen Receptor
- Antigen Receptor, Mo1
- Receptor, Mo1 Antigen
- Mo1 Glycoprotein Receptor
- Glycoprotein Receptor, Mo1
- Receptor, Mo1 Glycoprotein
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alpha M beta 2
- alpha-M beta-2, Integrin
- Complement 3 Receptor
- Receptor, Complement 3
- Mac-1 Antigen
- Mac 1 Antigen
- Adhesive Receptor Mac-1
- Mac-1 Adhesive Receptor
- Adhesive Receptor, Mac-1
- Mac 1 Adhesive Receptor
- Receptor, Mac-1 Adhesive
- Mac-1 Receptor
- Mac 1 Receptor
- Integrin alphaMbeta2
- alphaMbeta2, Integrin
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Below are MeSH descriptors whose meaning is more general than "Macrophage-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-1 Antigen".
This graph shows the total number of publications written about "Macrophage-1 Antigen" by people in this website by year, and whether "Macrophage-1 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage-1 Antigen" by people in Profiles.
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Johnson CM, O'Brien XM, Byrd AS, Parisi VE, Loosely AJ, Li W, Witt H, Faridi MH, LeFort CT, Gupta V, Kim M, Reichner JS. Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal ß-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response. J Immunol. 2017 01 01; 198(1):318-334.
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Smeekens SP, Gresnigt MS, Becker KL, Cheng SC, Netea SA, Jacobs L, Jansen T, van de Veerdonk FL, Williams DL, Joosten LA, Dinarello CA, Netea MG. An anti-inflammatory property of Candida albicans ß-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Cytokine. 2015 Feb; 71(2):215-22.
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Li J, Kim K, Hahm E, Molokie R, Hay N, Gordeuk VR, Du X, Cho J. Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation. J Clin Invest. 2014 Apr; 124(4):1483-96.
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Hahm E, Li J, Kim K, Huh S, Rogelj S, Cho J. Extracellular protein disulfide isomerase regulates ligand-binding activity of aMß2 integrin and neutrophil recruitment during vascular inflammation. Blood. 2013 May 09; 121(19):3789-800, S1-15.
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Maiguel D, Faridi MH, Wei C, Kuwano Y, Balla KM, Hernandez D, Barth CJ, Lugo G, Donnelly M, Nayer A, Moita LF, Schürer S, Traver D, Ruiz P, Vazquez-Padron RI, Ley K, Reiser J, Gupta V. Small molecule-mediated activation of the integrin CD11b/CD18 reduces inflammatory disease. Sci Signal. 2011 Sep 06; 4(189):ra57.
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Soloviev DA, Fonzi WA, Sentandreu R, Pluskota E, Forsyth CB, Yadav S, Plow EF. Identification of pH-regulated antigen 1 released from Candida albicans as the major ligand for leukocyte integrin alphaMbeta2. J Immunol. 2007 Feb 15; 178(4):2038-46.
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Forsyth CB, Mathews HL. Lymphocyte adhesion to Candida albicans. Infect Immun. 2002 Feb; 70(2):517-27.
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Keshavarzian A, Fusunyan RD, Jacyno M, Winship D, MacDermott RP, Sanderson IR. Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol. 1999 Mar; 94(3):704-12.
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Robinson CE, Kottapalli V, D'Astice M, Fields JZ, Winship D, Keshavarzian A. Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602.
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