"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
| Descriptor ID |
D015847
|
| MeSH Number(s) |
D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
|
| Concept/Terms |
Interleukin-4- Interleukin-4
- Interleukin 4
- B-Cell Growth Factor-1
- B Cell Growth Factor 1
- B-Cell Growth Factor-I
- B Cell Growth Factor I
- B-Cell Proliferating Factor
- B Cell Proliferating Factor
- B-Cell Stimulating Factor-1
- B Cell Stimulating Factor 1
- B-Cell Stimulatory Factor 1
- B-Cell Stimulatory Factor-1
- BCGF-1
- Binetrakin
- BSF-1
- IL-4
- IL4
- Mast Cell Growth Factor-2
- Mast Cell Growth Factor 2
- MCGF-2
- B Cell Stimulatory Factor-1
- B Cell Stimulatory Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Interleukin-4" by people in Profiles.
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Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study. Atherosclerosis. 2022 06; 351:18-25.
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Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. Arch Dermatol Res. 2021 Dec; 313(10):837-846.
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Anti-inflammatory effects of interleukin-4 on intervertebral disc cells. Spine J. 2020 01; 20(1):60-68.
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Schistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion. Infect Immun. 2013 Jan; 81(1):133-42.
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Protective effector memory CD4 T cells depend on ICOS for survival. PLoS One. 2011 Feb 18; 6(2):e16529.
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Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice. Arthritis Rheum. 2010 Oct; 62(10):2984-94.
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Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma. J Allergy Clin Immunol. 2010 Aug; 126(2):347-54.
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Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages. FASEB J. 2008 Nov; 22(11):4022-32.
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Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption. Arthritis Rheum. 2008 Aug; 58(8):2397-408.
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Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol Pharmacol. 2007 Oct; 72(4):934-46.