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Williams, David
One or more keywords matched the following items that are connected to Williams, David
Item TypeName
Concept Glutathione Reductase
Concept Glucosephosphate Dehydrogenase Deficiency
Concept Methionine Sulfoxide Reductases
Concept Oxidoreductases
Concept NADH, NADPH Oxidoreductases
Concept NADPH Oxidases
Concept Thioredoxin-Disulfide Reductase
Academic Article Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
Academic Article Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade.
Academic Article Identification of oxadiazoles as new drug leads for the control of schistosomiasis.
Academic Article A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase.
Academic Article Characterization of the methionine sulfoxide reductases of Schistosoma mansoni.
Academic Article Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects.
Academic Article Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
Academic Article Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni.
Academic Article Thioredoxin glutathione reductase: its role in redox biology and potential as a target for drugs against neglected diseases.
Academic Article On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.
Academic Article Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites.
Academic Article Proteomic profiling of nitrosative stress: protein S-oxidation accompanies S-nitrosylation.
Academic Article New praziquantel derivatives containing NO-donor furoxans and related furazans as active agents against Schistosoma mansoni.
Academic Article Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats.
Academic Article Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs.
Academic Article High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis.
Academic Article The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase.
Academic Article Oxadiazole 2-oxides are toxic to the human hookworm, Ancylostoma ceylanicum, however glutathione reductase is not the primary target.
Academic Article Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase.
Academic Article Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry.
Academic Article Ectopic suicide inhibition of thioredoxin glutathione reductase.
Academic Article Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis.
Academic Article Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments.
Academic Article Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.
Academic Article Impaired phagocytosis directs human monocyte activation in response to fungal derived ?-glucan particles.
Academic Article Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
Academic Article Descriptive Analysis of Transient-State Observations for Thioredoxin/Glutathione Reductase (Sec597Cys) from Schistosoma mansoni.
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  • Oxidoreductases