"Fibromodulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that contains 4 KERATAN SULFATE chains within the leucine repeat region. It interacts with COLLAGEN TYPE I and COLLAGEN TYPE II fibrils and may function to control the rate of EXTRACELLULAR MATRIX assembly. It also sequesters TRANSFORMING GROWTH FACTOR BETA in the extracellular matrix.
| Descriptor ID |
D000071235
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| MeSH Number(s) |
D09.698.735.700.813 D12.776.395.650.875.625 D12.776.860.300.806.813
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fibromodulin".
Below are MeSH descriptors whose meaning is more specific than "Fibromodulin".
This graph shows the total number of publications written about "Fibromodulin" by people in this website by year, and whether "Fibromodulin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibromodulin" by people in Profiles.
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Regulation of proteoglycan production by varying glucose concentrations controls fiber formation in tissue engineered menisci. Acta Biomater. 2019 12; 100:173-183.
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Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):10-6.
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TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage. Osteoarthritis Cartilage. 2003 Mar; 11(3):167-76.
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Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration. Spine (Phila Pa 1976). 2002 Oct 15; 27(20):2212-9.
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Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol. 2000 Aug; 157(2):423-33.
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Age-related changes in the structure of the keratan sulphate chains attached to fibromodulin isolated from articular cartilage. Biochem J. 1998 Mar 01; 330 ( Pt 2):753-7.
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Proteoglycans of human rotator cuff tendons. J Orthop Res. 1996 Jul; 14(4):518-25.
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Glycosaminoglycan addition to proteoglycans by articular chondrocytes--evidence for core protein-specific pathways. Arch Biochem Biophys. 1995 Jun 01; 319(2):383-92.
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Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage. Arthritis Rheum. 1995 May; 38(5):660-8.
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Biosynthetic mechanisms for the addition of polylactosamine to chondrocyte fibromodulin. J Biol Chem. 1993 Dec 15; 268(35):26634-44.