"Biglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan found in a variety of tissues including CAPILLARY ENDOTHELIUM; SKELETAL MUSCLE; CARTILAGE; BONE; and TENDONS. The protein contains two glycosaminoglycan chains and is similar in structure to DECORIN.
| Descriptor ID |
D058578
|
| MeSH Number(s) |
D09.698.735.700.500 D12.776.395.650.750.562 D12.776.395.650.875.250 D12.776.860.300.806.500
|
| Concept/Terms |
Biglycan- Biglycan
- Proteoglycan S1
- Bone Proteoglycan I
|
Below are MeSH descriptors whose meaning is more general than "Biglycan".
Below are MeSH descriptors whose meaning is more specific than "Biglycan".
This graph shows the total number of publications written about "Biglycan" by people in this website by year, and whether "Biglycan" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Biglycan" by people in Profiles.
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Biglycan Inhibits Capsaicin-Induced Substance P Release by Cultured Dorsal Root Ganglion Neurons. Am J Phys Med Rehabil. 2016 09; 95(9):656-62.
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Biglycan regulates the expression of EGF receptors through EGF signaling pathways in human articular chondrocytes. Connect Tissue Res. 2010 Oct; 51(5):347-58.
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Age-related changes in the extracellular matrix of nucleus pulposus and anulus fibrosus of human intervertebral disc. Spine (Phila Pa 1976). 2009 Jan 01; 34(1):10-6.
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Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels. J Orthop Res. 2003 Jul; 21(4):730-7.
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TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage. Osteoarthritis Cartilage. 2003 Mar; 11(3):167-76.
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Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration. Spine (Phila Pa 1976). 2002 Oct 15; 27(20):2212-9.
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Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am J Pathol. 2000 Aug; 157(2):423-33.
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Proteoglycan metabolism during repair of the ruptured medial collateral ligament in skeletally mature rabbits. Arch Biochem Biophys. 2000 Feb 01; 374(1):35-41.
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Large and small proteoglycans of osteoarthritic and rheumatoid articular cartilage. Arthritis Rheum. 1995 May; 38(5):660-8.