"Trefoil Factor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 59 amino acid (6.6 kDa) trefoil factor that contains a single trefoil domain. It is expressed in all tissues with MUCOUS MEMBRANES, including GOBLET CELLS of the SMALL INTESTINE and LARGE INTESTINE. It associates with MUCIN-2 in the small intestine and may regulate epithelial CELL MIGRATION and WOUND HEALING.
| Descriptor ID |
D000071165
|
| MeSH Number(s) |
D12.644.937.875
|
| Concept/Terms |
Trefoil Factor-3- Trefoil Factor-3
- Trefoil Factor 3
- TFF3 Peptide
- Intestinal Trefoil Factor
- Trefoil Factor, Intestinal
- TFF3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Trefoil Factor-3".
Below are MeSH descriptors whose meaning is more specific than "Trefoil Factor-3".
This graph shows the total number of publications written about "Trefoil Factor-3" by people in this website by year, and whether "Trefoil Factor-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
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Below are the most recent publications written about "Trefoil Factor-3" by people in Profiles.
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A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells. J Clin Invest. 1999 Dec; 104(11):1539-47.
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Goblet-cell-specific transcription of mouse intestinal trefoil factor gene results from collaboration of complex series of positive and negative regulatory elements. Biochem J. 1999 Jul 15; 341 ( Pt 2):461-72.
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Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein. J Biol Chem. 1998 Jan 30; 273(5):3060-7.