"Ouabain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
| Descriptor ID |
D010042
|
| MeSH Number(s) |
D04.210.500.155.580.130.750.600 D09.408.180.810.600
|
| Concept/Terms |
Ouabain- Ouabain
- G-Strophanthin
- G Strophanthin
- Acocantherin
- Acolongifloroside K
|
Below are MeSH descriptors whose meaning is more general than "Ouabain".
Below are MeSH descriptors whose meaning is more specific than "Ouabain".
This graph shows the total number of publications written about "Ouabain" by people in this website by year, and whether "Ouabain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ouabain" by people in Profiles.
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The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function. J Physiol. 2006 Sep 15; 575(Pt 3):845-54.
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Palytoxin disrupts cardiac excitation-contraction coupling through interactions with P-type ion pumps. Am J Physiol Cell Physiol. 2004 Aug; 287(2):C527-38.
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Stoichiometry and regulation of the Na-Ca exchanger in barnacle muscle cells. Ann N Y Acad Sci. 1991; 639:22-33.
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Effect of quinidine on differing sensitivities of Purkinje fibers and myocardium to inhibition of monovalent cation transport by digitalis in dogs. Am J Cardiol. 1983 Nov 01; 52(8):1123-6.
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Histamine antagonists as antiarrhythmic agents in ouabain cardiotoxicity in the cat. J Pharmacol Exp Ther. 1980 Aug; 214(2):375-80.
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The antiarrhythmic effects of quinidine and propranolol in the ouabain-intoxicated spinally transected cat. Eur J Pharmacol. 1979 Feb 15; 54(1-2):161-6.
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Neural basis for the genesis and control of digitalis arrhythmias. Cardiology. 1976; 61(1):50-60.