Group IV Phospholipases A2
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Group IV Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
    
			
			
				
				
					
						| Descriptor ID | D054513 | 
					
						| MeSH Number(s) | D08.811.277.352.100.680.750.937.625.249 | 
					
						| Concept/Terms | Group IV Phospholipases A2Group IV Phospholipases A2PLA2-IVPhospholipases A2, Group IVPLA(2)-IVGroup IV Cytosolic Phospholipase A2Phospholipase A2 IV
 Group IVB Phospholipase A2Group IVB Phospholipase A2Phospholipase A2-betaPhospholipase A2 betaPhospholipase A2, Group IVBCytosolic Phospholipase A2 betaGroup IVB Phospholipases A2
 Group IVC Phospholipase A2Group IVC Phospholipase A2Phospholipase A2, Group IVCCytosolic Phospholipase A2 gammacPLA2-gammacPLA2 gammaGroup IVC Phospholipases A2Phospholipase A2-gammaPhospholipase A2 gamma
 Group IVE Phospholipase A2Group IVE Phospholipase A2Group IVE Phospholipases A2Phospholipase A2, Group IVECytosolic Phospholipase A2 epsilon
 Group IVA Phospholipase A2Group IVA Phospholipase A2Cytosolic Phospholipase A2 alphaPhospholipase A2-alphaPhospholipase A2 alphaPhospholipase A(2)alphaPhospholipase A2 Group IVAcPLA2-alphacPLA2 alphaGroup IVA Phospholipases A2
 Group IVD Phospholipase A2Group IVD Phospholipase A2Group IVD Phospholipases A2Phospholipase A2, Group IVDCytosolic Phospholipase A2 delta
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				Below are MeSH descriptors whose meaning is more general than "Group IV Phospholipases A2".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Group IV Phospholipases A2".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Group IV Phospholipases A2" by people in this website by year, and whether "Group IV Phospholipases A2" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2006 | 0 | 1 | 1 | 
| 2022 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Group IV Phospholipases A2" by people in Profiles.
						
					
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								Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4. Mol Neurodegener. 2022 06 15; 17(1):42. 
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								Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol. 2007 Mar 01; 579(Pt 2):327-44.