Viral Regulatory and Accessory Proteins
"Viral Regulatory and Accessory Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of viral proteins that play indirect roles in the biological processes and activities of viruses. Included here are proteins that either regulate the expression of viral genes or are involved in modifying host cell functions. Many of the proteins in this category serve multiple functions.
| Descriptor ID |
D054334
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| MeSH Number(s) |
D12.776.964.925
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Viral Regulatory and Accessory Proteins".
Below are MeSH descriptors whose meaning is more specific than "Viral Regulatory and Accessory Proteins".
This graph shows the total number of publications written about "Viral Regulatory and Accessory Proteins" by people in this website by year, and whether "Viral Regulatory and Accessory Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Viral Regulatory and Accessory Proteins" by people in Profiles.
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CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells. AIDS Res Hum Retroviruses. 2017 02; 33(2):93-100.
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HIV-1 Vpu utilizes both cullin-RING ligase (CRL) dependent and independent mechanisms to downmodulate host proteins. Retrovirology. 2015 Jul 28; 12:65.
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Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx. Virology. 2015 Feb; 476:19-25.
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Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4? T cells. Cell Rep. 2014 Jun 26; 7(6):2019-30.
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Agnogene deletion in a novel pathogenic JC virus isolate impairs VP1 expression and virion production. PLoS One. 2013; 8(11):e80840.
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Human tetherin exerts strong selection pressure on the HIV-1 group N Vpu protein. PLoS Pathog. 2012 Dec; 8(12):e1003093.
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JC virus encephalopathy is associated with a novel agnoprotein-deletion JCV variant. PLoS One. 2012; 7(4):e35793.
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The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins. Viruses. 2011 07; 3(7):1091-111.
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Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe. 2010 Nov 18; 8(5):397-409.
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Roles of Vpr and Vpx in modulating the virus-host cell relationship. Mol Aspects Med. 2010 Oct; 31(5):398-406.