"Gene Products, nef" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
| Descriptor ID |
D015693
|
| MeSH Number(s) |
D12.776.964.775.362 D12.776.964.925.500
|
| Concept/Terms |
Gene Products, nef- Gene Products, nef
- Gene Product, nef
- nef Gene Product
- nef Protein
- 3'-orf Protein
- 3' orf Protein
- nef Gene Products
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, nef".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, nef".
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Below are the most recent publications written about "Gene Products, nef" by people in Profiles.
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Characteristics of HIV-1 Nef regions containing multiple CD8+ T cell epitopes: wealth of HLA-binding motifs and sensitivity to proteasome degradation. J Immunol. 2001 May 15; 166(10):6164-9.