Endoplasmic Reticulum-Associated Degradation
"Endoplasmic Reticulum-Associated Degradation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
| Descriptor ID |
D060746
|
| MeSH Number(s) |
G02.111.660.871.790.600.962.500 G02.111.691.600.850.500 G03.734.871.790.600.850.500 G05.308.670.600.850.500
|
| Concept/Terms |
Endoplasmic Reticulum-Associated Degradation- Endoplasmic Reticulum-Associated Degradation
- Degradation, Endoplasmic Reticulum-Associated
- Endoplasmic Reticulum Associated Degradation
- Reticulum-Associated Degradation, Endoplasmic
- ERAD Pathway
- ERAD Pathways
- Pathway, ERAD
- Pathways, ERAD
|
Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum-Associated Degradation".
Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum-Associated Degradation".
This graph shows the total number of publications written about "Endoplasmic Reticulum-Associated Degradation" by people in this website by year, and whether "Endoplasmic Reticulum-Associated Degradation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endoplasmic Reticulum-Associated Degradation" by people in Profiles.
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Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease. Am J Physiol Renal Physiol. 2018 03 01; 314(3):F471-F482.
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The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex. Mol Endocrinol. 2013 Dec; 27(12):2105-15.