Fas-Associated Death Domain Protein
"Fas-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
| Descriptor ID |
D053200
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| MeSH Number(s) |
D12.644.360.024.285.200 D12.644.360.024.500.124 D12.644.360.075.421.200 D12.776.157.057.018.200 D12.776.157.057.500.124 D12.776.476.024.320.550 D12.776.476.024.500.124 D12.776.476.075.421.200
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| Concept/Terms |
Fas-Associated Death Domain Protein- Fas-Associated Death Domain Protein
- Fas-Associating Protein with Death Domain
- Fas Associating Protein with Death Domain
- MORT1 Protein
- Fas Associated Death Domain Protein
- FADD Protein, Fas-Associating
- FADD Protein, Fas Associating
- Fas-Associating FADD Protein
- Fas-Associating Protein FADD
- FADD, Fas-Associating Protein
- Fas Associating Protein FADD
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Below are MeSH descriptors whose meaning is more general than "Fas-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas-Associated Death Domain Protein".
This graph shows the total number of publications written about "Fas-Associated Death Domain Protein" by people in this website by year, and whether "Fas-Associated Death Domain Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fas-Associated Death Domain Protein" by people in Profiles.
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Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample. Mol Neurodegener. 2017 03 20; 12(1):26.
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Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene. Cancer Res. 2008 Sep 15; 68(18):7352-61.
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Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations. Exp Dermatol. 2002 Dec; 11(6):573-83.