"Chromogranin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromogranin which was first isolated from CHROMAFFIN CELLS of the ADRENAL MEDULLA but is also found in other tissues and in many species including human, bovine, rat, mouse, and others. It is an acidic protein with 431 to 445 amino acid residues. It contains fragments that inhibit vasoconstriction or release of hormones and neurotransmitter, while other fragments exert antimicrobial actions.
| Descriptor ID |
D053379
|
| MeSH Number(s) |
D12.776.631.199.249
|
| Concept/Terms |
Chromogranin A- Chromogranin A
- Parathyroid Secretory Protein
- Secretory Protein, Parathyroid
- CHGA Protein
- Secretory Protein I, Parathyroid Gland
|
Below are MeSH descriptors whose meaning is more general than "Chromogranin A".
Below are MeSH descriptors whose meaning is more specific than "Chromogranin A".
This graph shows the total number of publications written about "Chromogranin A" by people in this website by year, and whether "Chromogranin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Chromogranin A" by people in Profiles.
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Preoperative serum chromogranin-a is predictive of survival in locoregional jejuno-ileal small bowel neuroendocrine tumors. Surgery. 2021 07; 170(1):106-113.
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Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate. Alcohol Clin Exp Res. 2017 Dec; 41(12):2100-2113.
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Neuroendocrine Tumors of the Breast. Arch Pathol Lab Med. 2017 Nov; 141(11):1577-1581.
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Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient. Mov Disord. 2007 Aug 15; 22(11):1630-3.
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Clinical improvement in parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin A or basic fibroblast growth factor in ventricular fluid. Exp Neurol. 1991 Mar; 111(3):276-81.
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Neuroendocrine differentiation in endocrine and nonendocrine lung carcinomas. Am J Clin Pathol. 1988 Dec; 90(6):641-52.
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Expression of neuroendocrine cell markers L-dopa decarboxylase, chromogranin A, and dense core granules in human tumors of endocrine and nonendocrine origin. Cancer Res. 1988 Jul 15; 48(14):4078-82.