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Presenilin-1

"Presenilin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Integral membrane protein of Golgi and endoplasmic reticulum. Its homodimer is an essential component of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. PSEN1 mutations cause early-onset ALZHEIMER DISEASE type 3 that may occur as early as 30 years of age in humans.


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This graph shows the total number of publications written about "Presenilin-1" by people in this website by year, and whether "Presenilin-1" was a major or minor topic of these publications.
Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2010 and 2012 and 2013 and 2015 and 2021
To see the data from this visualization as text, click here.
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