"Integrin beta3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
| Descriptor ID |
D039661
|
| MeSH Number(s) |
D12.776.543.750.705.408.200.750
|
| Concept/Terms |
Integrin beta3- Integrin beta3
- beta3, Integrin
- CD61 Antigen
- Antigen, CD61
- GPIIIa
- beta(3) Integrin
- Platelet Glycoprotein IIIa
- Glycoprotein IIIa, Platelet
- Platelet GPIIIa
- Antigens, CD61
- CD61 Antigens
- Platelet Membrane Glycoprotein IIIa
- beta3 Integrin
- Integrin, beta3
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta3".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta3".
This graph shows the total number of publications written about "Integrin beta3" by people in this website by year, and whether "Integrin beta3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin beta3" by people in Profiles.
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Podocyte Integrin-?3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy. J Am Soc Nephrol. 2020 08; 31(8):1762-1780.
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Monitoring suPAR levels in post-kidney transplant focal segmental glomerulosclerosis treated with therapeutic plasma exchange and rituximab. BMC Nephrol. 2018 12 17; 19(1):361.
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Recurrent Primary Focal Segmental Glomerulosclerosis Managed With Intensified Plasma Exchange and Concomitant Monitoring of Soluble Urokinase-Type Plasminogen Activator Receptor-Mediated Podocyte ?3-integrin Activation. Transplantation. 2015 Dec; 99(12):2593-7.
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Enhancement of ovarian tumor detection with av?3 integrin-targeted ultrasound molecular imaging agent in laying hens: a preclinical model of spontaneous ovarian cancer. Int J Gynecol Cancer. 2014 Jan; 24(1):19-28.
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Management of severe recurrent focal segmental glomerulosclerosis through circulating soluble urokinase receptor modification. Am J Ther. 2013 Mar-Apr; 20(2):226-9.
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The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury. J Mol Med (Berl). 2012 Dec; 90(12):1407-20.
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Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med. 2011 Jul 31; 17(8):952-60.
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Role of the beta-subunit arginine/lysine finger in integrin heterodimer formation and function. J Immunol. 2008 Feb 01; 180(3):1713-8.
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Role of phosphatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis. Am J Physiol Lung Cell Mol Physiol. 2005 Dec; 289(6):L1094-103.
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6-Hydroxydopamine-induced alterations in blood-brain barrier permeability. Eur J Neurosci. 2005 Sep; 22(5):1158-68.