"B7-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D018122
|
| MeSH Number(s) |
D12.776.467.150.100 D12.776.543.095.100 D23.050.301.285.100 D23.529.168.100
|
| Concept/Terms |
B7-1 Antigen- B7-1 Antigen
- B7 1 Antigen
- CD80 Antigen
- CD80 Antigens
- B7-1 Ligand
- B7 1 Ligand
- Ligand, B7-1
- B7-1 Costimulatory Molecule
- B7 1 Costimulatory Molecule
- Costimulatory Molecule, B7-1
- Antigen, B7-1
- Antigen, B7 1
- B-Cell Activation Antigen
- B Cell Activation Antigen
- Antigens, CD80
|
Below are MeSH descriptors whose meaning is more general than "B7-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-1 Antigen".
This graph shows the total number of publications written about "B7-1 Antigen" by people in this website by year, and whether "B7-1 Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "B7-1 Antigen" by people in Profiles.
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CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance: response. Pediatr Nephrol. 2014 Aug; 29(8):1467-8.
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Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2014 03 27; 370(13):1263-4.
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Role of podocyte B7-1 in diabetic nephropathy. J Am Soc Nephrol. 2014 Jul; 25(7):1415-29.
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CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol. 2014 Aug; 29(8):1363-71.
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Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med. 2013 Dec 19; 369(25):2416-23.
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CD80, suPAR and nephrotic syndrome in a case of NPHS2 mutation. Nefrologia. 2013; 33(5):727-31.
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Maximal 'CD80-uria' with minimal change. Kidney Int. 2010 Aug; 78(3):236-8.
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Soluble ions more than particulate cobalt-alloy implant debris induce monocyte costimulatory molecule expression and release of proinflammatory cytokines critical to metal-induced lymphocyte reactivity. J Biomed Mater Res A. 2010 Jun 15; 93(4):1312-21.
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Proteinuria: an enzymatic disease of the podocyte? Kidney Int. 2010 Apr; 77(7):571-80.
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Characterization of quantitative and functional innate immune parameters in HIV-1-infected Colombian children receiving stable highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2008 Dec 01; 49(4):348-57.