Systemic Inflammatory Response Syndrome
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Systemic Inflammatory Response Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever >38 degrees C or HYPOTHERMIA <36 degrees C; (2) TACHYCARDIA >90 beat/minute; (3) tachypnea >24 breaths/minute; (4) LEUKOCYTOSIS >12,000 cells/cubic mm or 10% immature forms. While usually related to infection, SIRS can also be associated with noninfectious insults such as TRAUMA; BURNS; or PANCREATITIS. If infection is involved, a patient with SIRS is said to have SEPSIS.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D018746
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						| MeSH Number(s) | 
						
							 C23.550.470.790 C23.550.835.900 
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						| Concept/Terms | 
						
							
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				Below are MeSH descriptors whose meaning is more general than "Systemic Inflammatory Response Syndrome".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Systemic Inflammatory Response Syndrome".
				
					
						- Systemic Inflammatory Response Syndrome
 - Sepsis
 
					
				 
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Systemic Inflammatory Response Syndrome" by people in this website by year, and whether "Systemic Inflammatory Response Syndrome" was a major or minor topic of these publications. 
				
					
                    To see the data from this visualization as text, 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1995 | 2 | 0 | 2 | 
| 1997 | 1 | 0 | 1 | 
| 2005 | 0 | 1 | 1 | 
| 2007 | 1 | 0 | 1 | 
| 2011 | 1 | 0 | 1 | 
| 2013 | 2 | 0 | 2 | 
| 2016 | 1 | 0 | 1 | 
| 2017 | 2 | 2 | 4 | 
| 2018 | 1 | 0 | 1 | 
| 2021 | 3 | 0 | 3 | 
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				Below are the most recent publications written about "Systemic Inflammatory Response Syndrome" by people in Profiles.
						
					
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Acute Large Vessel Ischemic Stroke in Patients With COVID-19-Related Multisystem Inflammatory Syndrome. Pediatr Neurol. 2022 01; 126:104-107.
															
								 
							
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SHEA Pediatric Leadership Council commentary: Personal protective equipment during care of children with multisystem inflammatory syndrome in children (MIS-C). Infect Control Hosp Epidemiol. 2021 09; 42(9):1108-1110.
															
								 
							
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Multisystem inflammatory syndrome in children with COVID-19. Am J Emerg Med. 2021 Nov; 49:148-152.
															
								 
							
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Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU. Am J Respir Crit Care Med. 2018 10 01; 198(7):903-913.
															
								 
							
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Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM). Crit Care Med. 2017 Dec; 45(12):2089-2098.
															
								 
							
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Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. Intensive Care Med. 2017 Dec; 43(12):1751-1763.
															
								 
							
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Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM). Intensive Care Med. 2017 Dec; 43(12):1781-1792.
															
								 
							
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To SIRS With Love-An Open Letter. Crit Care Med. 2017 04; 45(4):736-738.
															
								 
							
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The New Sepsis Definitions: Implications for Critical Care Practitioners. Am J Crit Care. 2016 Sep; 25(5):457-64.
															
								 
							
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Systemic inflammatory response syndrome (SIRS): where did it come from and is it still relevant today? Virulence. 2014 Jan 01; 5(1):20-6.