"Digoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
| Descriptor ID |
D004077
|
| MeSH Number(s) |
D04.210.500.155.580.130.500.436 D04.210.500.155.580.130.688 D09.408.180.261.436
|
| Concept/Terms |
Digoxine Nativelle- Digoxine Nativelle
- Nativelle, Digoxine
- Hemigoxine Nativelle
- Nativelle, Hemigoxine
Lanoxin- Lanoxin
- Lanoxin-PG
- Lanoxin PG
- Lenoxin
|
Below are MeSH descriptors whose meaning is more general than "Digoxin".
Below are MeSH descriptors whose meaning is more specific than "Digoxin".
This graph shows the total number of publications written about "Digoxin" by people in this website by year, and whether "Digoxin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Digoxin" by people in Profiles.
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Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis. Glia. 2022 10; 70(10):1950-1970.
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Falsely Elevated Digoxin Levels in Patients on Enzalutamide. Circ Heart Fail. 2020 07; 13(7):e007008.
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Digoxin therapy for atrial fibrillation in the twenty-first century. Am J Ther. 2014 Sep-Oct; 21(5):325-6.
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Treatment of systolic heart failure in the elderly: an evidence-based review. Ann Pharmacother. 2010 Oct; 44(10):1604-14.
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The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function. J Physiol. 2006 Sep 15; 575(Pt 3):845-54.
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Drug therapy in pediatric cardiology and the role of digoxin in pediatric congestive heart failure. Pediatr Cardiol. 2004 Nov-Dec; 25(6):621.
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Selection bias in electrophysiologically-guided therapy of sustained ventricular tachyarrhythmias. J Clin Epidemiol. 1994 Jan; 47(1):49-57.
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Comparative study of encainide and quinidine in the treatment of ventricular arrhythmias. J Am Coll Cardiol. 1986 Jan; 7(1):9-16.
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Effect of quinidine on differing sensitivities of Purkinje fibers and myocardium to inhibition of monovalent cation transport by digitalis in dogs. Am J Cardiol. 1983 Nov 01; 52(8):1123-6.
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The effect of altered renal perfusion pressure on clearance of digoxin. Circulation. 1980 Mar; 61(3):521-5.