"Least-Squares Analysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D016018
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						| MeSH Number(s) | 
						
							 E05.318.740.750.400 N05.715.360.750.695.440 N06.850.520.830.750.400 
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						| Concept/Terms | 
						
							Least-Squares Analysis- Least-Squares Analysis
 - Analyses, Least-Squares
 - Least Squares Analysis
 - Least-Squares Analyses
 - Analysis, Least-Squares
 - Analysis, Least Squares
 - Least Squares
 
  
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				Below are MeSH descriptors whose meaning is more general than "Least-Squares Analysis".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Least-Squares Analysis".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Least-Squares Analysis" by people in this website by year, and whether "Least-Squares Analysis" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1995 | 0 | 1 | 1 | 
| 2008 | 0 | 2 | 2 | 
| 2011 | 0 | 1 | 1 | 
| 2015 | 0 | 3 | 3 | 
| 2016 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Least-Squares Analysis" by people in Profiles.
						
					
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Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials. Sci Transl Med. 2016 Jan 13; 8(321):321ra5.
															
								 
							
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Gastrointestinal Symptoms and Altered Intestinal Permeability Induced by Combat Training Are Associated with Distinct Metabotypic Changes. J Proteome Res. 2015 Nov 06; 14(11):4734-42.
															
								 
							
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Effects of the Learning Curve on Efficacy of Radiofrequency Ablation for Barrett's Esophagus. Gastroenterology. 2015 Oct; 149(4):890-6.e2.
															
								 
							
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Elevational gradients in ?-diversity reflect variation in the strength of local community assembly mechanisms across spatial scales. PLoS One. 2015; 10(3):e0121458.
															
								 
							
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Can people remain engaged and vigorous in the face of trauma? Palestinians in the West Bank and Gaza. Psychiatry. 2012; 75(1):60-75.
															
								 
							
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Kernelized partial least squares for feature reduction and classification of gene microarray data. BMC Syst Biol. 2011; 5 Suppl 3:S13.
															
								 
							
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Anatomic variation in the elastic anisotropy of cortical bone tissue in the human femur. J Mech Behav Biomed Mater. 2009 Jul; 2(3):255-63.
															
								 
							
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Neighborhood environment and adherence to a walking intervention in African American women. Health Educ Behav. 2009 Feb; 36(1):167-81.
															
								 
							
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Qureshi grading scheme predicts subsequent volume of brain infarction following intra-arterial thrombolysis in patients with acute anterior circulation ischemic stroke. J Neuroimaging. 2008 Jul; 18(3):262-7.
															
								 
							
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Clitoral therapy device for treatment of sexual dysfunction in irradiated cervical cancer patients. Int J Radiat Oncol Biol Phys. 2005 Mar 15; 61(4):1078-86.