"Molecular Chaperones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
| Descriptor ID |
D018832
|
| MeSH Number(s) |
D12.776.580
|
| Concept/Terms |
Molecular Chaperones- Molecular Chaperones
- Molecular Chaperone
- Chaperone, Molecular
- Chaperones, Molecular
|
Below are MeSH descriptors whose meaning is more general than "Molecular Chaperones".
Below are MeSH descriptors whose meaning is more specific than "Molecular Chaperones".
This graph shows the total number of publications written about "Molecular Chaperones" by people in this website by year, and whether "Molecular Chaperones" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Molecular Chaperones" by people in Profiles.
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Activation of PPARa Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis. J Neurosci. 2023 03 08; 43(10):1814-1829.
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Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020 11 01; 77(11):1172-1180.
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Cyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates. Sci Rep. 2017 03 27; 7:45214.
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.
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KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection. PLoS Pathog. 2016 06; 12(6):e1005700.
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NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472.
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Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Structure. 2012 Mar 07; 20(3):429-39.
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Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Mol Cell. 2011 Mar 18; 41(6):672-81.
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Angiotensin I-converting enzyme Gln1069Arg mutation impairs trafficking to the cell surface resulting in selective denaturation of the C-domain. PLoS One. 2010 May 03; 5(5):e10438.
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Point of view. Spine (Phila Pa 1976). 2002 Feb 15; 27(4):368.