Transcription Factor 7-Like 2 Protein
"Transcription Factor 7-Like 2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN. Transcription factor 7-like 2 protein plays an important role in the embryogenesis of the PANCREAS and ISLET CELLS.
| Descriptor ID |
D058118
|
| MeSH Number(s) |
D12.776.260.730.875 D12.776.660.235.400.800.875 D12.776.664.235.400.800.875 D12.776.930.875.875
|
| Concept/Terms |
Transcription Factor 7-Like 2 Protein- Transcription Factor 7-Like 2 Protein
- Transcription Factor 7 Like 2 Protein
- T-Cell-Specific Transcription Factor 4
- T Cell Specific Transcription Factor 4
- T Cell Transcription Factor 4
- TCF7L2 Transcription Factor
- Transcription Factor, TCF7L2
- T Cell Factor 4
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor 7-Like 2 Protein".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor 7-Like 2 Protein".
This graph shows the total number of publications written about "Transcription Factor 7-Like 2 Protein" by people in this website by year, and whether "Transcription Factor 7-Like 2 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor 7-Like 2 Protein" by people in Profiles.
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Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. J Immunol. 2010 Aug 15; 185(4):2013-9.
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Human immunodeficiency virus-restricted replication in astrocytes and the ability of gamma interferon to modulate this restriction are regulated by a downstream effector of the Wnt signaling pathway. J Virol. 2007 Jun; 81(11):5864-71.
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Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. Biochem Biophys Res Commun. 2005 Mar 04; 328(1):227-34.