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Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.
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Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma.
Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma. Int J Oncol. 2011 Jan; 38(1):105-12.
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PubMed
subject areas
Acetylation
Benzoquinones
Cell Line, Tumor
Cyclin-Dependent Kinase Inhibitor p21
Gene Expression Regulation, Neoplastic
Genes, myc
Genes, p53
HSP90 Heat-Shock Proteins
Humans
Lactams, Macrocyclic
Neuroblastoma
N-Myc Proto-Oncogene Protein
Nuclear Proteins
Oncogene Proteins
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-myc
Transfection
Tubulin
Tumor Suppressor Protein p53
authors with profiles
Joshua J. Jacobs