"Myelin Basic Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant cytosolic protein that plays a critical role in the structure of multilamellar myelin. Myelin basic protein binds to the cytosolic sides of myelin cell membranes and causes a tight adhesion between opposing cell membranes.
| Descriptor ID |
D004676
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| MeSH Number(s) |
D12.776.543.620.540 D12.776.631.580.510
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myelin Basic Protein".
Below are MeSH descriptors whose meaning is more specific than "Myelin Basic Protein".
This graph shows the total number of publications written about "Myelin Basic Protein" by people in this website by year, and whether "Myelin Basic Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myelin Basic Protein" by people in Profiles.
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Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2009 Apr 15; 182(8):5013-23.
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Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem. 2007 Nov 02; 282(44):32222-32.
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Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radic Biol Med. 2005 Sep 15; 39(6):823-31.
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Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. J Biol Chem. 2005 Sep 23; 280(38):32609-17.
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Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline. Neurosci Res. 2004 Jan; 48(1):93-100.
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Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells. J Biol Chem. 2003 Jun 20; 278(25):22424-31.
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Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol. 2003 Apr 01; 170(7):3874-82.
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Myelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. J Biol Chem. 2002 Oct 18; 277(42):39327-33.
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Calcium-dependent protein kinase-C activity in human adrenocortical neoplasms, hyperplastic adrenals, and normal adrenocortical tissue. J Clin Endocrinol Metab. 1994 Sep; 79(3):736-9.