"Myelin Basic Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant cytosolic protein that plays a critical role in the structure of multilamellar myelin. Myelin basic protein binds to the cytosolic sides of myelin cell membranes and causes a tight adhesion between opposing cell membranes.
| Descriptor ID |
D004676
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| MeSH Number(s) |
D12.776.543.620.540 D12.776.631.580.510
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myelin Basic Protein".
Below are MeSH descriptors whose meaning is more specific than "Myelin Basic Protein".
This graph shows the total number of publications written about "Myelin Basic Protein" by people in this website by year, and whether "Myelin Basic Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myelin Basic Protein" by people in Profiles.
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Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death. ASN Neuro. 2013 Feb 06; 5(1):e00105.
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Gender-specific expression of beta1 integrin of VLA-4 in myelin basic protein-primed T cells: implications for gender bias in multiple sclerosis. J Immunol. 2010 Jun 01; 184(11):6103-13.
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Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. J Immunol. 2010 Feb 15; 184(4):1799-809.
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Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2009 Apr 15; 182(8):5013-23.
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NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci. 2008 Jun 25; 28(26):6670-8.
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Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem. 2007 Nov 02; 282(44):32222-32.
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Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2007 Jul 01; 179(1):275-83.
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Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radic Biol Med. 2005 Sep 15; 39(6):823-31.
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Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. J Biol Chem. 2005 Sep 23; 280(38):32609-17.
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Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline. Neurosci Res. 2004 Jan; 48(1):93-100.