"HL-60 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)
| Descriptor ID |
D018922
|
| MeSH Number(s) |
A11.251.210.190.465 A11.251.860.180.465 A11.627.340.360.500
|
| Concept/Terms |
HL-60 Cells- HL-60 Cells
- HL 60 Cells
- HL-60 Cell
- HL60 Cells
- Cell, HL60
- Cells, HL60
- HL60 Cell
|
Below are MeSH descriptors whose meaning is more general than "HL-60 Cells".
Below are MeSH descriptors whose meaning is more specific than "HL-60 Cells".
This graph shows the total number of publications written about "HL-60 Cells" by people in this website by year, and whether "HL-60 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 2 | 2 |
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Below are the most recent publications written about "HL-60 Cells" by people in Profiles.
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Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60. J Cell Biochem. 2005 Mar 01; 94(4):695-707.
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Activation of Raf1 and the ERK pathway in response to l-ascorbic acid in acute myeloid leukemia cells. Cell Signal. 2005 Jan; 17(1):111-9.
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L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms. Int J Biochem Cell Biol. 2004 Nov; 36(11):2180-95.
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L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60. J Cell Biochem. 2004 Oct 01; 93(2):257-70.
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Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells. J Cell Biochem. 2004 Apr 01; 91(5):973-86.
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Increased cytosol Ca(2+) and type 1 programmed cell death in Bcl-2-positive U937 but not in Bcl-2-negative PC-3 and Panc-1 cells induced by the 5-lipoxygenase inhibitor MK 886. Prostaglandins Leukot Essent Fatty Acids. 2002 Apr; 66(4):443-52.
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Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine IL-6: a general role for inflammation? FASEB J. 2000 Aug; 14(11):1499-507.
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Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways. Cell Immunol. 1999 May 25; 194(1):36-46.
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Temperature dependence of voltage-gated H+ currents in human neutrophils, rat alveolar epithelial cells, and mammalian phagocytes. J Gen Physiol. 1998 Oct; 112(4):503-22.
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Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine. Oncol Res. 1998; 10(4):185-92.