Choline O-Acetyltransferase
"Choline O-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of acetylcholine from acetyl-CoA and choline. EC 2.3.1.6.
| Descriptor ID |
D002795
|
| MeSH Number(s) |
D08.811.913.050.134.180
|
| Concept/Terms |
Choline O-Acetyltransferase- Choline O-Acetyltransferase
- Choline O Acetyltransferase
- O-Acetyltransferase, Choline
- Choline Acetylase
- Acetylase, Choline
- Choline Acetyltransferase
- Acetyltransferase, Choline
|
Below are MeSH descriptors whose meaning is more general than "Choline O-Acetyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Choline O-Acetyltransferase".
This graph shows the total number of publications written about "Choline O-Acetyltransferase" by people in this website by year, and whether "Choline O-Acetyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Choline O-Acetyltransferase" by people in Profiles.
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No evidence for association between 19 cholinergic genes and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 05; 144B(6):715-23.
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Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys. Ann Neurol. 2006 Aug; 60(2):264-8.
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Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease. Arch Neurol. 2005 Mar; 62(3):425-30.
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Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys. J Comp Neurol. 2004 Apr 26; 472(2):193-207.
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Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system. J Comp Neurol. 2003 Aug 25; 463(3):341-57.
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Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Arch Neurol. 2003 Aug; 60(8):1143-8.
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Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology. J Alzheimers Dis. 2003 Feb; 5(1):39-48.
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Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol. 2002 Feb; 51(2):145-55.
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Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase. Brain Res. 1999 Dec 04; 849(1-2):253-74.
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Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. J Comp Neurol. 1999 Sep 06; 411(4):693-704.