"X-Box Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.
Descriptor ID |
D000071717
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MeSH Number(s) |
D12.776.260.108.937 D12.776.930.127.937
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Concept/Terms |
X-Box Binding Protein 1- X-Box Binding Protein 1
- X Box Binding Protein 1
- TREB5 Protein
- Tax-Responsive Element-Binding Protein 5
- Tax Responsive Element Binding Protein 5
- XBP-1 Protein
- XBP 1 Protein
- TREB-5 Protein
- TREB 5 Protein
- XBP2 Protein
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Below are MeSH descriptors whose meaning is more general than "X-Box Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "X-Box Binding Protein 1".
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Below are the most recent publications written about "X-Box Binding Protein 1" by people in Profiles.
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Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. Blood. 2017 09 21; 130(12):1445-1455.
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Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy. Nat Commun. 2015 Mar 10; 6:6496.