 Interleukin-10
"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
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| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
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| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 3 | 0 | 3 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 2 | 2 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Roy R, Zayas J, Mohamed MF, Aboonabi A, Delgado K, Wallace J, Bayat M, Kuzel TM, Reiser J, Shafikhani SH. IL-10 Dysregulation Underlies Chemokine Insufficiency, Delayed Macrophage Response, and Impaired Healing in Diabetic Wounds. J Invest Dermatol. 2022 03; 142(3 Pt A):692-704.e14.
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Newman JH, Chesson CB, Herzog NL, Bommareddy PK, Aspromonte SM, Pepe R, Estupinian R, Aboelatta MM, Buddhadev S, Tarabichi S, Lee M, Li S, Medina DJ, Giurini EF, Gupta KH, Guevara-Aleman G, Rossi M, Nowicki C, Abed A, Goldufsky JW, Broucek JR, Redondo RE, Rotter D, Jhawar SR, Wang SJ, Kohlhapp FJ, Kaufman HL, Thomas PG, Gupta V, Kuzel TM, Reiser J, Paras J, Kane MP, Singer EA, Malhotra J, Denzin LK, Sant'Angelo DB, Rabson AB, Lee LY, Lasfar A, Langenfeld J, Schenkel JM, Fidler MJ, Ruiz ES, Marzo AL, Rudra JS, Silk AW, Zloza A. Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer. Proc Natl Acad Sci U S A. 2020 01 14; 117(2):1119-1128.
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Brocca-Cofano E, Kuhrt D, Siewe B, Xu C, Haret-Richter GS, Craigo J, Labranche C, Montefiori DC, Landay A, Apetrei C, Pandrea I. Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction. J Virol. 2017 12 01; 91(23).
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Gebe JA, Yadava K, Ruppert SM, Marshall P, Hill P, Falk BA, Sweere JM, Han H, Kaber G, Harten IA, Medina C, Mikecz K, Ziegler SF, Balaji S, Keswani SG, Perez VA, Butte MJ, Nadeau K, Altemeier WA, Fanger N, Bollyky PL. Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance. Am J Respir Cell Mol Biol. 2017 01; 56(1):109-120.
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Zhang Y, Chee A, Shi P, Adams SL, Markova DZ, Anderson DG, Smith HE, Deng Y, Plastaras CT, An HS. Intervertebral Disc Cells Produce Interleukins Found in Patients with Back Pain. Am J Phys Med Rehabil. 2016 06; 95(6):407-15.
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Jolly M, Francis S, Aggarwal R, Mikolaitis RA, Niewold TB, Chubinskaya S, Block JA, Scanzello C, Sequeira W. Serum free light chains, interferon-alpha, and interleukins in systemic lupus erythematosus. Lupus. 2014 Aug; 23(9):881-8.
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Siewe B, Wallace J, Rygielski S, Stapleton JT, Martin J, Deeks SG, Landay A. Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs. PLoS One. 2014; 9(4):e92934.
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Thiruppathi M, Sheng JR, Li L, Prabhakar BS, Meriggioli MN. Recombinant IgG2a Fc (M045) multimers effectively suppress experimental autoimmune myasthenia gravis. J Autoimmun. 2014 Aug; 52:64-73.
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Hodowanec AC, Brady KE, Gao W, Kincaid SL, Plants J, Bahk M, Landay AL, Huhn GD. Characterization of CD4? T-cell immune activation and interleukin 10 levels among HIV, hepatitis C virus, and HIV/HCV-coinfected patients. J Acquir Immune Defic Syndr. 2013 Nov 01; 64(3):232-40.
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Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, Demarais PM, French AL, Landay A. Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8? T cell function in vitro. J Leukoc Biol. 2013 May; 93(5):811-8.
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