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Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo.
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Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo.
Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo. Nat Commun. 2021 09 10; 12(1):5382.
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PubMed
subject areas
alpha-Synuclein
Animals
Cells, Cultured
Disease Models, Animal
Dopaminergic Neurons
Humans
Lewy Body Disease
Mice
Mice, Knockout
Microglia
Multiple System Atrophy
Mutagenesis, Site-Directed
Mutation
Myeloid Differentiation Factor 88
NF-kappa B
Parkinson Disease
Primary Cell Culture
Promoter Regions, Genetic
Signal Transduction
Toll-Like Receptor 2
authors with profiles
Malabendu Jana
Susanta Mondal
Kalipada Pahan