 Matrix Metalloproteinases
"Matrix Metalloproteinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.
| Descriptor ID |
D020782
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| MeSH Number(s) |
D08.811.277.656.300.480.525 D08.811.277.656.675.374.525
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinases".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinases".
This graph shows the total number of publications written about "Matrix Metalloproteinases" by people in this website by year, and whether "Matrix Metalloproteinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 2 | 0 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 1 | 2 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Matrix Metalloproteinases" by people in Profiles.
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Miller RE, Ishihara S, Tran PB, Golub SB, Last K, Miller RJ, Fosang AJ, Malfait AM. An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI Insight. 2018 03 22; 3(6).
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Huang G, Chubinskaya S, Liao W, Loeser RF. Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes. Osteoarthritis Cartilage. 2017 09; 25(9):1505-1515.
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Gopalakrishnan M, Silva-Palacios F, Taytawat P, Pant R, Klein L. Role of inflammatory mediators in the pathogenesis of plaque rupture. J Invasive Cardiol. 2014 Sep; 26(9):484-92.
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Pant R, Marok R, Klein LW. Pathophysiology of coronary vascular remodeling: relationship with traditional risk factors for coronary artery disease. Cardiol Rev. 2014 Jan-Feb; 22(1):13-6.
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Yan D, Chen D, Shen J, Xiao G, van Wijnen AJ, Im HJ. Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synovium. J Cell Physiol. 2013 Feb; 228(2):447-56.
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Ellman MB, Kim JS, An HS, Chen D, KC R, An J, Dittakavi T, van Wijnen AJ, Cs-Szabo G, Li X, Xiao G, An S, Kim SG, Im HJ. Toll-like receptor adaptor signaling molecule MyD88 on intervertebral disk homeostasis: in vitro, ex vivo studies. Gene. 2012 Sep 01; 505(2):283-90.
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Shieh HS, Tomasselli AG, Mathis KJ, Schnute ME, Woodard SS, Caspers N, Williams JM, Kiefer JR, Munie G, Wittwer A, Malfait AM, Tortorella MD. Structure analysis reveals the flexibility of the ADAMTS-5 active site. Protein Sci. 2011 Apr; 20(4):735-44.
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Sun HB, Andarawis-Puri N, Li Y, Fung DT, Lee JY, Wang VM, Basta-Pljakic J, Leong DJ, Sereysky JB, Ros SJ, Klug RA, Braman J, Schaffler MB, Jepsen KJ, Flatow EL. Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons. J Orthop Res. 2010 Oct; 28(10):1380-6.
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Wise JK, Sena K, Vranizan K, Pollock JF, Healy KE, Hughes WF, Sumner DR, Virdi AS. Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regeneration. PLoS One. 2010 Oct 01; 5(10).
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Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Sch?nke M, Kurz B. Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2. Cell Tissue Res. 2010 Apr; 340(1):179-88.
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