N-Formylmethionine Leucyl-Phenylalanine
"N-Formylmethionine Leucyl-Phenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
Descriptor ID |
D009240
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MeSH Number(s) |
D02.886.030.676.450.440 D12.125.166.676.450.440 D12.644.456.400 D23.125.320.685 D23.125.685
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Concept/Terms |
N-Formylmethionine Leucyl-Phenylalanine- N-Formylmethionine Leucyl-Phenylalanine
- Leucyl-Phenylalanine, N-Formylmethionine
- N Formylmethionine Leucyl Phenylalanine
- Formylmethionyl-Leucyl-Phenylalanine
- Formylmethionyl Leucyl Phenylalanine
- N-Formyl-Methionyl-Leucyl-Phenylalanine
- N Formyl Methionyl Leucyl Phenylalanine
- Formylmet-Leu-Phe
- Formylmet Leu Phe
- Formylmethionylleucylphenylalanine
Formylmethionyl Peptide- Formylmethionyl Peptide
- Peptide, Formylmethionyl
- N-Formylated Peptide
- N Formylated Peptide
- Peptide, N-Formylated
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Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine Leucyl-Phenylalanine".
Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine Leucyl-Phenylalanine".
This graph shows the total number of publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in this website by year, and whether "N-Formylmethionine Leucyl-Phenylalanine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 | 1996 | 0 | 1 | 1 | 1997 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2020 | 0 | 1 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in Profiles.
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Hamilton JL, Mohamed MF, Witt BR, Wimmer MA, Shafikhani SH. Therapeutic assessment of N-formyl-methionyl-leucyl-phenylalanine (fMLP) in reducing periprosthetic joint infection. Eur Cell Mater. 2021 08 26; 42:122-138.
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Martinez L, Li X, Ramos-Echazabal G, Faridi H, Zigmond ZM, Santos Falcon N, Hernandez DR, Shehadeh SA, Velazquez OC, Gupta V, Vazquez-Padron RI. A Genetic Model of Constitutively Active Integrin CD11b/CD18. J Immunol. 2020 11 01; 205(9):2545-2553.
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Musset B, Morgan D, Cherny VV, MacGlashan DW, Thomas LL, R?os E, DeCoursey TE. A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):11020-5.
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Morgan D, Cherny VV, Finnegan A, Bollinger J, Gelb MH, DeCoursey TE. Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol. 2007 Mar 01; 579(Pt 2):327-44.
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Gabali AM, Anzinger JJ, Spear GT, Thomas LL. Activation by inflammatory stimuli increases neutrophil binding of human immunodeficiency virus type 1 and subsequent infection of lymphocytes. J Virol. 2004 Oct; 78(19):10833-6.
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Robinson CE, Kottapalli V, D'Astice M, Fields JZ, Winship D, Keshavarzian A. Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602.
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Keshavarzian A, Haydek JM, Jacyno M, Holmes EW, Harford F. Modulatory effects of the colonic milieu on neutrophil oxidative burst: a possible pathogenic mechanism of ulcerative colitis. J Lab Clin Med. 1997 Aug; 130(2):216-25.
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Everitt EA, Malik AB, Hendey B. Fibronectin enhances the migration rate of human neutrophils in vitro. J Leukoc Biol. 1996 Aug; 60(2):199-206.
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Hendey B, Lawson M, Marcantonio EE, Maxfield FR. Intracellular calcium and calcineurin regulate neutrophil motility on vitronectin through a receptor identified by antibodies to integrins alphav and beta3. Blood. 1996 Mar 01; 87(5):2038-48.
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Sarfati I, Lopes D, Murphy EA, Rao S, Cohen JR. Inhibition by protease inhibitors of chemotaxis induced by elastin-derived peptides. J Surg Res. 1996 Feb 15; 61(1):84-8.
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