N-Formylmethionine Leucyl-Phenylalanine
"N-Formylmethionine Leucyl-Phenylalanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
| Descriptor ID |
D009240
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| MeSH Number(s) |
D02.886.030.676.450.440 D12.125.072.050.685.445 D12.125.142.666.500 D12.125.166.676.450.440 D12.644.456.400 D23.125.685
|
| Concept/Terms |
N-Formylmethionine Leucyl-Phenylalanine- N-Formylmethionine Leucyl-Phenylalanine
- Leucyl-Phenylalanine, N-Formylmethionine
- N Formylmethionine Leucyl Phenylalanine
- Formylmethionyl-Leucyl-Phenylalanine
- Formylmethionyl Leucyl Phenylalanine
- N-Formyl-Methionyl-Leucyl-Phenylalanine
- N Formyl Methionyl Leucyl Phenylalanine
- Formylmet-Leu-Phe
- Formylmet Leu Phe
- Formylmethionylleucylphenylalanine
Formylmethionyl Peptide- Formylmethionyl Peptide
- Peptide, Formylmethionyl
- N-Formylated Peptide
- N Formylated Peptide
- Peptide, N-Formylated
|
Below are MeSH descriptors whose meaning is more general than "N-Formylmethionine Leucyl-Phenylalanine".
Below are MeSH descriptors whose meaning is more specific than "N-Formylmethionine Leucyl-Phenylalanine".
This graph shows the total number of publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in this website by year, and whether "N-Formylmethionine Leucyl-Phenylalanine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "N-Formylmethionine Leucyl-Phenylalanine" by people in Profiles.
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Therapeutic assessment of N-formyl-methionyl-leucyl-phenylalanine (fMLP) in reducing periprosthetic joint infection. Eur Cell Mater. 2021 08 26; 42:122-138.
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A Genetic Model of Constitutively Active Integrin CD11b/CD18. J Immunol. 2020 11 01; 205(9):2545-2553.
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A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils. Proc Natl Acad Sci U S A. 2008 Aug 05; 105(31):11020-5.
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Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity. J Physiol. 2007 Mar 01; 579(Pt 2):327-44.
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Activation by inflammatory stimuli increases neutrophil binding of human immunodeficiency virus type 1 and subsequent infection of lymphocytes. J Virol. 2004 Oct; 78(19):10833-6.
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Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602.
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Modulatory effects of the colonic milieu on neutrophil oxidative burst: a possible pathogenic mechanism of ulcerative colitis. J Lab Clin Med. 1997 Aug; 130(2):216-25.
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Fibronectin enhances the migration rate of human neutrophils in vitro. J Leukoc Biol. 1996 Aug; 60(2):199-206.
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Intracellular calcium and calcineurin regulate neutrophil motility on vitronectin through a receptor identified by antibodies to integrins alphav and beta3. Blood. 1996 Mar 01; 87(5):2038-48.
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Inhibition by protease inhibitors of chemotaxis induced by elastin-derived peptides. J Surg Res. 1996 Feb 15; 61(1):84-8.