Thioredoxin-Disulfide Reductase
"Thioredoxin-Disulfide Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
| Descriptor ID |
D013880
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| MeSH Number(s) |
D08.811.682.667.750 D12.776.331.971
|
| Concept/Terms |
Thioredoxin-Disulfide Reductase- Thioredoxin-Disulfide Reductase
- Reductase, Thioredoxin-Disulfide
- Thioredoxin Disulfide Reductase
- Thioredoxin Reductase (NADPH)
- Thioredoxin Reductase
- Reductase, Thioredoxin
- NADP-Thioredoxin Reductase
- NADP Thioredoxin Reductase
- Reductase, NADP-Thioredoxin
- NADPH-Thioredoxin Reductase
- NADPH Thioredoxin Reductase
- Reductase, NADPH-Thioredoxin
|
Below are MeSH descriptors whose meaning is more general than "Thioredoxin-Disulfide Reductase".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxin-Disulfide Reductase".
This graph shows the total number of publications written about "Thioredoxin-Disulfide Reductase" by people in this website by year, and whether "Thioredoxin-Disulfide Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thioredoxin-Disulfide Reductase" by people in Profiles.
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Descriptive Analysis of Transient-State Observations for Thioredoxin/Glutathione Reductase (Sec597Cys) from Schistosoma mansoni. Biochemistry. 2023 05 02; 62(9):1497-1508.
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Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol. 2022 05; 51:102278.
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Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med. 2020 02 01; 147:200-211.
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Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J. 2015 Aug; 282(16):3199-217.
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A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase. Assay Drug Dev Technol. 2008 Aug; 6(4):551-5.
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Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin. Int J Parasitol. 2002 Sep; 32(10):1285-92.
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The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase. Mol Biochem Parasitol. 2002 Apr 30; 121(1):129-39.
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Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase. Infect Immun. 2001 Feb; 69(2):1134-41.