Glomerulosclerosis, Focal Segmental
"Glomerulosclerosis, Focal Segmental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
| Descriptor ID |
D005923
|
| MeSH Number(s) |
C12.777.419.570.363.660 C13.351.968.419.570.363.640
|
| Concept/Terms |
Glomerulosclerosis, Focal Segmental- Glomerulosclerosis, Focal Segmental
- Segmental Glomerulosclerosis, Focal
- Glomerulosclerosis, Focal
- Focal Glomerulosclerosis
- Focal Segmental Glomerulosclerosis
- Glomerulonephritis, Focal Sclerosing
- Focal Sclerosing Glomerulonephritides
- Focal Sclerosing Glomerulonephritis
- Glomerulonephritides, Focal Sclerosing
- Sclerosing Glomerulonephritides, Focal
- Sclerosing Glomerulonephritis, Focal
Hyalinosis, Segmental Glomerular- Hyalinosis, Segmental Glomerular
- Glomerular Hyalinosis, Segmental
- Segmental Glomerular Hyalinosis
- Hyalinosis, Segmental
- Segmental Hyalinosis
|
Below are MeSH descriptors whose meaning is more general than "Glomerulosclerosis, Focal Segmental".
Below are MeSH descriptors whose meaning is more specific than "Glomerulosclerosis, Focal Segmental".
This graph shows the total number of publications written about "Glomerulosclerosis, Focal Segmental" by people in this website by year, and whether "Glomerulosclerosis, Focal Segmental" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glomerulosclerosis, Focal Segmental" by people in Profiles.
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The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5. Kidney Int. 2023 06; 103(6):1056-1062.
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The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases. Kidney Int. 2020 04; 97(4):753-764.
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Contribution of Coiled-Coil Assembly to Ca2+/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes. J Am Soc Nephrol. 2019 09; 30(9):1587-1603.
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MeSsAGe risk score: tool for renal biopsy decision in steroid-dependent nephrotic syndrome. Pediatr Res. 2019 03; 85(4):477-483.
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ACTH Gel in Resistant Focal Segmental Glomerulosclerosis After Kidney Transplantation. Transplantation. 2019 01; 103(1):202-209.
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Monitoring suPAR levels in post-kidney transplant focal segmental glomerulosclerosis treated with therapeutic plasma exchange and rituximab. BMC Nephrol. 2018 12 17; 19(1):361.
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Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria. Sci Rep. 2018 10 03; 8(1):14723.
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Rituximab and Therapeutic Plasma Exchange in Recurrent Focal Segmental Glomerulosclerosis Postkidney Transplantation. Transplantation. 2018 03; 102(3):e115-e120.
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Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease. Am J Physiol Renal Physiol. 2018 03 01; 314(3):F471-F482.
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suPAR and chronic kidney disease-a podocyte story. Pflugers Arch. 2017 Aug; 469(7-8):1017-1020.