 Cyclic GMP
"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
| Descriptor ID |
D006152
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| MeSH Number(s) |
D03.438.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
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| Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2006 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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Andersen JB, Hultqvist LD, Jansen CU, Jakobsen TH, Nilsson M, Rybtke M, Uhd J, Fritz BG, Seifert R, Berthelsen J, Nielsen TE, Qvortrup K, Givskov M, Tolker-Nielsen T. Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms. NPJ Biofilms Microbiomes. 2021 07 09; 7(1):59.
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Groizeleau J, Rybtke M, Andersen JB, Berthelsen J, Liu Y, Yang L, Nielsen TE, Kaever V, Givskov M, Tolker-Nielsen T. The anti-cancerous drug doxorubicin decreases the c-di-GMP content in Pseudomonas aeruginosa but promotes biofilm formation. Microbiology (Reading). 2016 10; 162(10):1797-1807.
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Assadi F, Sharbaf FG. Sildenafil for the Treatment of Congenital Nephrogenic Diabetes Insipidus. Am J Nephrol. 2015; 42(1):65-9.
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Walther S, Pluteanu F, Renz S, Nikonova Y, Maxwell JT, Yang LZ, Schmidt K, Edwards JN, Wakula P, Groschner K, Maier LS, Spiess J, Blatter LA, Pieske B, Kockskämper J. Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H689-700.
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Christensen LD, van Gennip M, Rybtke MT, Wu H, Chiang WC, Alhede M, Høiby N, Nielsen TE, Givskov M, Tolker-Nielsen T. Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria. Infect Immun. 2013 Aug; 81(8):2705-13.
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Thorpe RB, Stockman SL, Williams JM, Lincoln TM, Pearce WJ. Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries. Am J Physiol Regul Integr Comp Physiol. 2013 May 01; 304(9):R734-43.
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Rybtke MT, Borlee BR, Murakami K, Irie Y, Hentzer M, Nielsen TE, Givskov M, Parsek MR, Tolker-Nielsen T. Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Aug; 78(15):5060-9.
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Pearce WJ, Williams JM, White CR, Lincoln TM. Effects of chronic hypoxia on soluble guanylate cyclase activity in fetal and adult ovine cerebral arteries. J Appl Physiol (1985). 2009 Jul; 107(1):192-9.
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Narayan P, Yeatman M, Caputo M, Capoun R, Ciulli F, Jeremy JY, Angelini GD. Saphenous vein harvest with the Mayo extraluminal dissector: is endothelial function preserved? J Thorac Cardiovasc Surg. 2009 Aug; 138(2):508-10.
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Brahmachari S, Fung YK, Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci. 2006 May 03; 26(18):4930-9.
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