 Aspartic Acid
"Aspartic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
| Descriptor ID |
D001224
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| MeSH Number(s) |
D12.125.067.500 D12.125.119.170 D12.125.427.040
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aspartic Acid".
Below are MeSH descriptors whose meaning is more specific than "Aspartic Acid".
This graph shows the total number of publications written about "Aspartic Acid" by people in this website by year, and whether "Aspartic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2011 | 1 | 2 | 3 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 |
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Below are the most recent publications written about "Aspartic Acid" by people in Profiles.
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DeCoursey TE. CrossTalk proposal: Proton permeation through HV 1 requires transient protonation of a conserved aspartate in the S1 transmembrane helix. J Physiol. 2017 11 15; 595(22):6793-6795.
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DeCoursey TE. Rebuttal from Thomas E. DeCoursey. J Physiol. 2017 11 15; 595(22):6801.
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Dudev T, Musset B, Morgan D, Cherny VV, Smith SM, Mazmanian K, DeCoursey TE, Lim C. Selectivity Mechanism of the Voltage-gated Proton Channel, HV1. Sci Rep. 2015 May 08; 5:10320.
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Musset B, Smith SM, Rajan S, Morgan D, Cherny VV, Decoursey TE. Aspartate?112 is the selectivity filter of the human voltage-gated proton channel. Nature. 2011 Oct 23; 480(7376):273-7.
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Lamar M, Foy CML, Beacher F, Daly E, Poppe M, Archer N, Prasher V, Murphy KC, Morris RG, Simmons A, Lovestone S, Murphy DGM. Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease. Neuroimage. 2011 Jul 01; 57(1):63-68.
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Krauss D, Eisenberg B, Gillespie D. Selectivity sequences in a model calcium channel: role of electrostatic field strength. Eur Biophys J. 2011 Jun; 40(6):775-82.
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Wang Y, Xu L, Pasek DA, Gillespie D, Meissner G. Probing the role of negatively charged amino acid residues in ion permeation of skeletal muscle ryanodine receptor. Biophys J. 2005 Jul; 89(1):256-65.
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Katz-Brull R, Lenkinski RE, Du Pasquier RA, Koralnik IJ. Elevation of myoinositol is associated with disease containment in progressive multifocal leukoencephalopathy. Neurology. 2004 Sep 14; 63(5):897-900.
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Roitberg B, Khan N, Tuccar E, Kompoliti K, Chu Y, Alperin N, Kordower JH, Emborg ME. Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study. Neurol Res. 2003 Jan; 25(1):68-78.
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Longley BJ, Metcalfe DD, Tharp M, Wang X, Tyrrell L, Lu SZ, Heitjan D, Ma Y. Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis. Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1609-14.
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