"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
|
| MeSH Number(s) |
G05.308.203.374
|
| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
|
Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 3 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Amelioration of Autoimmune Arthritis in Mice Treated With the DNA Methyltransferase Inhibitor 5'-Azacytidine. Arthritis Rheumatol. 2019 08; 71(8):1265-1275.
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GRP78-mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells. Mol Oncol. 2018 09; 12(9):1498-1512.
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Role of galectin-1 in urinary bladder urothelial carcinoma cell invasion through the JNK pathway. Cancer Sci. 2016 Oct; 107(10):1390-1398.
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Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons. Cell Stem Cell. 2015 Dec 03; 17(6):735-747.
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Long-term silencing of intersectin-1s in mouse lungs by repeated delivery of a specific siRNA via cationic liposomes. Evaluation of knockdown effects by electron microscopy. J Vis Exp. 2013 Jun 21; (76).
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Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells. Mol Cancer. 2012 Jun 18; 11:27.
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Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis. J Pathol. 2012 Mar; 226(4):645-53.
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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):17773-8.
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Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvasc Res. 2011 Sep; 82(2):105-12.
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An a-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons. Brain Res. 2011 Jun 13; 1395:94-107.