 Apolipoprotein E3
"Apolipoprotein E3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human, Apo E3 is a 299-amino acid protein with a cysteine at the 112 and an arginine at the 158 position. It is involved with the transport of TRIGLYCERIDES; PHOSPHOLIPIDS; CHOLESTEROL; and CHOLESTERYL ESTERS in and out of the cells.
| Descriptor ID |
D053318
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| MeSH Number(s) |
D10.532.091.500.500 D12.776.070.400.500.500 D12.776.521.120.500.500
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| Concept/Terms |
Apolipoprotein E3- Apolipoprotein E3
- Apo E3
- APOE-epsilon 3
- APOE epsilon 3
- Isoapolipoprotein E3
- ApoE3
- Apolipoprotein E-3
- Apolipoprotein E 3
- Apolipoprotein E-epsilon3
- Apolipoprotein E epsilon3
- Apo E-3
- Apo E 3
- APOE-epsilon3
- APOE epsilon3
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein E3".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein E3".
This graph shows the total number of publications written about "Apolipoprotein E3" by people in this website by year, and whether "Apolipoprotein E3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apolipoprotein E3" by people in Profiles.
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Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA. TOMM40'523 variant and cognitive decline in older persons with APOE e3/3 genotype. Neurology. 2017 Feb 14; 88(7):661-668.
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Li YJ, Hauser MA, Scott WK, Martin ER, Booze MW, Qin XJ, Walter JW, Nance MA, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Goetz CG, Small GW, Mastaglia F, Haines JL, Pericak-Vance MA, Vance JM. Apolipoprotein E controls the risk and age at onset of Parkinson disease. Neurology. 2004 Jun 08; 62(11):2005-9.
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Wilson RS, Bienias JL, Berry-Kravis E, Evans DA, Bennett DA. The apolipoprotein E epsilon 2 allele and decline in episodic memory. J Neurol Neurosurg Psychiatry. 2002 Dec; 73(6):672-7.
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