 Trypsin
"Trypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4.
| Descriptor ID |
D014357
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| MeSH Number(s) |
D08.811.277.656.300.760.895 D08.811.277.656.959.350.895
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin".
Below are MeSH descriptors whose meaning is more specific than "Trypsin".
This graph shows the total number of publications written about "Trypsin" by people in this website by year, and whether "Trypsin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1986 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsin" by people in Profiles.
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Mashiatulla M, Moran MM, Chan D, Li J, Freedman JD, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. Murine articular cartilage morphology and compositional quantification with high resolution cationic contrast-enhanced µCT. J Orthop Res. 2017 12; 35(12):2740-2748.
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Anzinger JJ, Mezo I, Ji X, Gabali AM, Thomas LL, Spear GT. HIV infection of mononuclear cells is calcium-dependent. Virus Res. 2006 Dec; 122(1-2):183-8.
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Buyn T, Dudeja P, Harris JE, Ou D, Seed T, Sawlani D, Meng J, Bonomi P, Anderson KM. A 5-lipoxygenase inhibitor at micromolar concentration raises intracellular calcium in U937 cells prior to their physiologic cell death. Prostaglandins Leukot Essent Fatty Acids. 1997 Jan; 56(1):69-77.
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Vogel KG, Sandy JD, Pogány G, Robbins JR. Aggrecan in bovine tendon. Matrix Biol. 1994 Mar; 14(2):171-9.
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Hunt P, Hokom MM, Wiemann B, Leven RM, Arakawa T. Megakaryocyte proplatelet-like process formation in vitro is inhibited by serum prothrombin, a process which is blocked by matrix-bound glycosaminoglycans. Exp Hematol. 1993 Feb; 21(2):372-81.
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Flannery C, Stanescu V, Mörgelin M, Boynton R, Gordy J, Sandy J. Variability in the G3 domain content of bovine aggrecan from cartilage extracts and chondrocyte cultures. Arch Biochem Biophys. 1992 Aug 15; 297(1):52-60.
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Block JA, Inerot SE, Kimura JH. Heterogeneity of keratan sulfate substituted on human chondrocytic large proteoglycans. J Biol Chem. 1992 Apr 15; 267(11):7245-52.
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Flannery CR, Lark MW, Sandy JD. Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage. J Biol Chem. 1992 Jan 15; 267(2):1008-14.
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Sandy JD, Flannery CR, Boynton RE, Neame PJ. Isolation and characterization of disulfide-bonded peptides from the three globular domains of aggregating cartilage proteoglycan. J Biol Chem. 1990 Dec 05; 265(34):21108-13.
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Bishop LJ, Cohen FS, Davidson VL, Cramer WA. Chemical modification of the two histidine and single cysteine residues in the channel-forming domain of colicin E1. J Membr Biol. 1986; 92(3):237-45.
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